Journal
PHARMACOGNOSY RESEARCH
Volume 7, Issue 1, Pages 57-65Publisher
MEDKNOW PUBLICATIONS & MEDIA PVT LTD
DOI: 10.4103/0974-8490.147209
Keywords
Essential oil; lavandin; lavandula hybrida; response surface method; static-dynamic steps; supercritical carbon dioxide
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Funding
- North Khorasan University of Medical Sciences
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Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Materials and Methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5 degrees C, 120 min (static: 8x15), 24 min (dynamic: 8x3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2 degrees C, 14 min (static), 121.1 min (dynamic). Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.
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