Journal
BLOOD PURIFICATION
Volume 36, Issue 3-4, Pages 274-279Publisher
KARGER
DOI: 10.1159/000355397
Keywords
Hyponatremia; Acute kidney injury; Hemodialysis; Continuous renal replacement therapies; Osmotic demyelination syndrome
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Rapid correction of severe hyponatremia can result in osmotic demyelination syndrome. Patients with severe hyponatremia and renal failure requiring dialysis pose a therapeutic challenge since the use of conventional intermittent hemodialysis will result in a rapid correction of the serum sodium level. We report the case of a 52-year-old woman with extreme hyponatremia and severe acute kidney injury, who was successfully treated with continuous venovenous hemodialysis using a modified dialysate solution with a low sodium concentration that was adjusted on a daily basis. (C) 2013 S. Karger AG, Basel
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