Journal
EUROPEAN THYROID JOURNAL
Volume 4, Issue 1, Pages 62-64Publisher
KARGER
DOI: 10.1159/000371548
Keywords
Induced hypothyroidism; Rhabdomyolysis; Statin therapy; Recombinant human thyrotropin
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Mild elevation of creatine kinase (CK) is common in untreated hypothyroidism, but severe myositis and overt rhabdomyolysis are rare. Similarly, muscle pain and CK elevation are potential side effects of statin therapy, yet rhabdomyolysis is likewise rare in the absence of medication interactions adversely affecting statin metabolism. The coexistence of statin therapy and hypothyroid states may synergistically increase the risk of myopathy. We describe a case of rhabdomyolysis attributable to induced hypothyroidism in a patient on chronic statin medication who was anticipating adjuvant radioiodine (131 I) therapy for a thyroid carcinoma (C) 2015 European Thyroid Association Published by S. Karger AG, Basel
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