Journal
CURRENT GREEN CHEMISTRY
Volume 2, Issue 2, Pages 170-191Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/2213346101666141202234329
Keywords
Carbon-carbon bonds; carbon-heteroatom bonds; copper; directing groups; functionalization; green chemistry; unactivated C-H bonds
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Funding
- Project of Science Technology Department of Zhejiang Province [2013C31119]
- Natural Science Foundation of Zhejiang Povince [LY13B020004]
- Zhejiang Apeloa Medical Technology Co. Ltd.
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The strategy of employing directing groups in C-H activation appears to be a big success in today's chemical synthesis due to its high efficiency and environmental friendly process. As various methodologies have been developed by using copper, this widespread and cheap catalyst has also played an important role in C-H activation. This review focuses on copper involved C-H activation assisted by directing groups developed in recent years, with the aim of providing a complementary to existing reviews.
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