Journal
EPILEPSY & BEHAVIOR CASE REPORTS
Volume 3, Issue -, Pages 36-38Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ebcr.2015.03.002
Keywords
22q11.2 deletion syndrome; Hyperprolinemia; Mental retardation; Epilepsy; Interictal psychosis; Phenytoin-induced hypocalcemia; DiGeorge syndrome
Categories
Ask authors/readers for more resources
In addition to causing polymalformative syndrome, 22q11.2 deletion can lead to various neuropsychiatric disorders includingmental retardation, psychosis, and epilepsy. However, fewreports regarding epilepsy-related psychosis in 22q11.2 deletion syndrome (22q11.2DS) exist. We describe the clinical characteristics and course of 22q11.2DS in a Japanese patient with comorbid mild mental retardation, childhood-onset localization-related epilepsy, and adult-onset, interictal schizophrenia-like psychosis. From a diagnostic viewpoint, early detection of impaired intellectual functioning and hyperprolinemia in patientswith epilepsy with 22q11.2DS may be helpful in predicting the developmental timing of interictal psychosis. Froma therapeutic viewpoint, special attention needs to be paid to phenytoin-induced hypocalcemia in this syndrome. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available