Journal
BREAST CANCER-BASIC AND CLINICAL RESEARCH
Volume 9, Issue -, Pages 23-34Publisher
SAGE PUBLICATIONS LTD
DOI: 10.4137/BCBCR.S25460
Keywords
breast cancer; metastasis; metastatic traits; targeted therapy; precision medicine
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Funding
- Susan G. Komen
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Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant improvement in current therapies in extending patient life, 30-40% of patients may eventually suffer from distant relapse and succumb to the disease. Consequently, a deeper understanding of the metastasis biology is key to developing better treatment strategies and achieving long-lasting therapeutic efficacies against breast cancer. This review covers recent breakthroughs in the discovery of various metastatic traits that contribute to the metastasis cascade of breast cancer, which may provide novel avenues for therapeutic targeting.
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