3.8 Article

MYB3Rs, plant homologs of Myb oncoproteins, control cell cycle-regulated transcription and form DREAM-like complexes

Journal

TRANSCRIPTION-AUSTIN
Volume 6, Issue 5, Pages 106-111

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/21541264.2015.1109746

Keywords

Arabidopsis; cell cycle; cell division; Myb; multiprotein complex; transcription factor

Funding

  1. BBSRC [BB/D017599/1] Funding Source: UKRI
  2. Biotechnology and Biological Sciences Research Council [BB/D017599/1] Funding Source: Medline
  3. Grants-in-Aid for Scientific Research [26660290, 26113509] Funding Source: KAKEN

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Plant MYB3R transcription factors, homologous to Myb oncoproteins, regulate the genes expressed at G2 and M phases in the cell cycle. Recent studies showed that MYB3Rs constitute multiprotein complexes that may correspond to animal complexes known as DREAM or dREAM. Discovery of the putative homologous complex in plants uncovered their significant varieties in structure, function, dynamics, and heterogeneity, providing insight into conserved and diversified aspects of cell cycle-regulated gene transcription.

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