Related references
Note: Only part of the references are listed.Group I and II mammalian PAKs have different modes of activation by Cdc42
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p21-Activated Kinases Are Required for Transformation in a Cell-Based Model of Neurofibromatosis Type 2
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BLOOD (2009)
Fanca-/- hematopoietic stem cells demonstrate a mobilization defect which can be overcome by administration of the Rac inhibitor NSC23766
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HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
PAK signaling in oncogenesis
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ONCOGENE (2009)
Scaffolding function of PAK in the PDK1-Akt pathway
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NATURE CELL BIOLOGY (2008)
P21-activated kinase is required for mitotic progression and regulates Plk1
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ONCOGENE (2008)
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PLOS ONE (2008)
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
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BLOOD (2008)
Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
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IMMUNITY (2006)
CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-HSP27 pathway
Simon Rousseau et al.
CELLULAR SIGNALLING (2006)
The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization
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EXPERIMENTAL HEMATOLOGY (2006)
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization
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NATURE MEDICINE (2005)
SDF-1 synergistically enhances IL-3-induced activation of the Raf-1/MEK/Erk signaling pathway through activation of Rac and its effector Pak kinases to promote hematopoiesis and chemotaxis
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CELLULAR SIGNALLING (2005)
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils
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NATURE IMMUNOLOGY (2004)
Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
Y Gu et al.
SCIENCE (2003)
The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2mnull mice
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LEUKEMIA (2002)
PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway
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ONCOGENE (2002)
Interaction between PAK and Nck: a template for Nck targets and role of PAK autophosphorylation
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MOLECULAR AND CELLULAR BIOLOGY (2000)