Related references
Note: Only part of the references are listed.P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment
Abdel Kareem Azab et al.
BLOOD (2012)
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
Abdel Kareem Azab et al.
BLOOD (2012)
Monoclonal antibody-based therapy as a new treatment strategy in multiple myeloma
N. W. C. J. van de Donk et al.
LEUKEMIA (2012)
Multiple myeloma: 2011 update on diagnosis, risk-stratification, and management
S. Vincent Rajkumar
AMERICAN JOURNAL OF HEMATOLOGY (2011)
Pathogenesis of Myeloma
Kenneth C. Anderson et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion
Paola Neri et al.
BLOOD (2011)
The clinical utility and prognostic value of multiparameter flow cytometry immunophenotyping in light-chain amyloidosis
Bruno Paiva et al.
BLOOD (2011)
The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications
Klaus Podar et al.
BRITISH JOURNAL OF HAEMATOLOGY (2011)
Tumor Metastasis: Molecular Insights and Evolving Paradigms
Scott Valastyan et al.
CELL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
Yusuke Shiozawa et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Soft-Tissue Plasmacytomas in Multiple Myeloma: Incidence, Mechanisms of Extramedullary Spread, and Treatment Approach
Joan Blade et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
Mei Yang et al.
MOLECULAR CANCER (2011)
Effects of zoledronic acid versus clodronic acid on skeletal morbidity in patients with newly diagnosed multiple myeloma (MRC Myeloma IX): secondary outcomes from a randomised controlled trial
Gareth J. Morgan et al.
LANCET ONCOLOGY (2011)
The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma
S. K. Martin et al.
LEUKEMIA (2011)
The biology of cancer metastasis
Isaiah J. Fidler
SEMINARS IN CANCER BIOLOGY (2011)
Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug
Jinsong Hu et al.
BLOOD (2010)
AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective
James E. Talmadge et al.
CANCER RESEARCH (2010)
Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis
Nobuyoshi Kosaka et al.
CANCER SCIENCE (2010)
A therapeutic role for targeting c-Myc/Hif-1-dependent signaling pathways
Klaus Podar et al.
CELL CYCLE (2010)
miR-31 A crucial overseer of tumor metastasis and other emerging roles
Scott Valastyan et al.
CELL CYCLE (2010)
Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
Xin Lu et al.
CLINICAL CANCER RESEARCH (2010)
P53 deletion may drive the clinical evolution and treatment response in multiple myeloma
Lucia Lopez-Anglada et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2010)
Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
Nobuyoshi Kosaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells
S. Colla et al.
LEUKEMIA (2010)
Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management
R. A. Kyle et al.
LEUKEMIA (2010)
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
Marc H. G. P. Raaijmakers et al.
NATURE (2010)
Cancer Cells in Transit: The Vascular Interactions of Tumor Cells
Konstantinos Konstantopoulos et al.
Annual Review of Biomedical Engineering (2009)
Src as a therapeutic target in men with prostate cancer and bone metastases
Fred Saad
BJU INTERNATIONAL (2009)
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma
Abdel Kareem Azab et al.
BLOOD (2009)
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
Abdel Kareem Azab et al.
BLOOD (2009)
Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study
Ola Landgren et al.
BLOOD (2009)
Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target
Dharminder Chauhan et al.
CANCER CELL (2009)
Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
John M. L. Ebos et al.
CANCER CELL (2009)
被撤回的出版物: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis (Retracted article. See vol. 161, pg. 417, 2015)
Scott Valastyan et al.
CELL (2009)
MicrorNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis
Scott Valastyan et al.
CELL CYCLE (2009)
Syndecan-1 Is Required for Robust Growth, Vascularization, and Metastasis of Myeloma Tumors in Vivo
Yekaterina B. Khotskaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Bone marrow microenvironment and the identification of new targets for myeloma therapy
K. Podar et al.
LEUKEMIA (2009)
p53 nuclear accumulation is associated with extramedullary progression of multiple myeloma
Neil Sheth et al.
LEUKEMIA RESEARCH (2009)
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
Cristina Lo Celso et al.
NATURE (2009)
Heparanase Regulates Levels of Syndecan-1 in the Nucleus
Ligong Chen et al.
PLOS ONE (2009)
Cancer Stem Cells, Hypoxia and Metastasis
Richard P. Hill et al.
SEMINARS IN RADIATION ONCOLOGY (2009)
Membrane vesicles as conveyors of immune responses
Clotilde Thery et al.
NATURE REVIEWS IMMUNOLOGY (2009)
The metastatic niche: adapting the foreign soil
Bethan Psaila et al.
NATURE REVIEWS CANCER (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
Metastasis: from dissemination to organ-specific colonization
Don X. Nguyen et al.
NATURE REVIEWS CANCER (2009)
Stem-cell ecology and stem cells in motion
Thalia Papayannopoulou et al.
BLOOD (2008)
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
Tamer T. Onder et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Stem cell trafficking in tissue development, growth, and disease
Diana J. Laird et al.
CELL (2008)
TWIST activation by hypoxia inducible factor-1 (HIF-1)
Muh-Hwa Yang et al.
CELL CYCLE (2008)
MicroRNAs as regulators of epithelial-mesenchymal transition
Philip. A. Gregory et al.
CELL CYCLE (2008)
Human tumor-derived exosomes down-modulate NKG2D expression
Aled Clayton et al.
JOURNAL OF IMMUNOLOGY (2008)
Circadian rhythms - Stem cells traffic in time
David T. Scadden
NATURE (2008)
Exosomes Derived from M-Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo
Pramod K. Giri et al.
PLOS ONE (2008)
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis
Manav Korpal et al.
RNA BIOLOGY (2008)
Endothelial and hematopoietic progenitor cells (EPCs and HPCs): Hand in hand fate determining partners for cancer cells
Sueleyman Erguen et al.
STEM CELL REVIEWS (2008)
Markers of epithelial-mesenchymal transition and epithelial differentiation in sarcomatoid carcinoma: Utility in the differential diagnosis with sarcoma
Justin M. M. Cates et al.
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2008)
The malignant clone and the bone-marrow environment
Klaus Podar et al.
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY (2007)
Monoclonal Gammopathy of undetermined significance and smoldering multiple myeloma
Robert A. Kyle et al.
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2007)
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment
Carl R. Walkley et al.
CELL (2007)
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma
Yazan Alsayed et al.
BLOOD (2007)
Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo
Shmuel Yaccoby et al.
BLOOD (2007)
Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma
S. Vincent Rajkumar et al.
BLOOD REVIEWS (2007)
Macrofocal multiple myeloma in young patients: A distinct entity with favorable prognosis
Meletios Athanasios Dimopoulos et al.
LEUKEMIA & LYMPHOMA (2006)
Exosomes: A common pathway for a specialized function
Guillaume van Niel et al.
JOURNAL OF BIOCHEMISTRY (2006)
The stem-cell niche as an entity of action
DT Scadden
NATURE (2006)
The stem cell niches in bone
T Yin et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
A study of the biological receptor activator of nuclear factor-κB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer
JJ Body et al.
CLINICAL CANCER RESEARCH (2006)
Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function
CR Liu et al.
JOURNAL OF IMMUNOLOGY (2006)
Circulating plasma cells detected by flow cytometry as a predictor of survival in 302 patients with newly diagnosed multiple myeloma
GS Nowakowski et al.
BLOOD (2005)
Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation
N Giuliani et al.
BLOOD (2005)
Molecular pathogenesis and a consequent classification of multiple myeloma
PL Bergsagel et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model
E Van Valckenborgh et al.
LEUKEMIA (2005)
Prognostic value of circulating plasma cells in monoclonal gammopathy of undetermined significance
S Kumar et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
M Kucia et al.
STEM CELLS (2005)
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment
DA Sipkins et al.
NATURE (2005)
Regulation of skeletal development by the Runx family of transcription factors
T Komori
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Circulating endothelial progenitor cells in multiple myeloma:: implications and significance
H Zhang et al.
BLOOD (2005)
Targeting signalling pathways for the treatment of multiple myeloma
K Podar et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2005)
Incorporation of CXCR4 into membrane hpid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient
M Wysoczynski et al.
BLOOD (2005)
Mechanisms of disease: Mechanisms of bone metastasis
GD Roodman
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Integrin α4β1 involvement in stromal cell-derived factor-1α-promoted myeloma cell transendothelial migration and adhesion:: role of cAMP and the actin cytoskeleton in adhesion
M Parmo-Cabañas et al.
EXPERIMENTAL CELL RESEARCH (2004)
TGF-β signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
NA Bhowmick et al.
SCIENCE (2004)
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
S Douma et al.
NATURE (2004)
CXCR4 regulates growth of both primary and metastatic breast cancer
MCP Smith et al.
CANCER RESEARCH (2004)
Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry
R Mears et al.
PROTEOMICS (2004)
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
J Yang et al.
CELL (2004)
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis
ST Avecilla et al.
NATURE MEDICINE (2004)
Anoikis
AJ Valentijn et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
Drug therapy: Multiple myeloma
RA Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
IL-6 regulates CD44 cell surface expression on human myeloma cells
T Vincent et al.
LEUKEMIA (2004)
Osteoblastic cells regulate the haematopoietic stem cell niche
LM Calvi et al.
NATURE (2003)
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver
O Kollet et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
A multigenic program mediating breast cancer metastasis to bone
YB Kang et al.
CANCER CELL (2003)
L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration
ZQ Ding et al.
BLOOD (2003)
Prognostic value of angiogenesis in solitary bone plasmacytoma
S Kumar et al.
BLOOD (2003)
Role of the bone marrow microenvironment in multiple myeloma
GD Roodman
JOURNAL OF BONE AND MINERAL RESEARCH (2002)
Dissemination and growth of cancer cells in metastatic sites
AF Chambers et al.
NATURE REVIEWS CANCER (2002)
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
I Petit et al.
NATURE IMMUNOLOGY (2002)
Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
G Andreola et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/ζ complex
N Blanchard et al.
JOURNAL OF IMMUNOLOGY (2002)
A long-term study of prognosis in monoclonal gammopathy of undetermined significance
RA Kyle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
S Yaccoby et al.
BRITISH JOURNAL OF HAEMATOLOGY (2002)
Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1
F Sanz-Rodríguez et al.
BLOOD (2001)
Adhesion to fibronectin via β1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR)
LA Hazlehurst et al.
ONCOGENE (2000)
The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function
K Thirunavukkarasu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)