Related references
Note: Only part of the references are listed.Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
Shilpee Dutt et al.
BLOOD (2011)
Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome
Kelly A. McGowan et al.
BLOOD (2011)
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
Pekka Jaako et al.
BLOOD (2011)
Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine
Manuela Giachelia et al.
LEUKEMIA RESEARCH (2011)
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells
G. Donati et al.
ONCOGENE (2011)
Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
Taichun Qin et al.
PLOS ONE (2011)
Failure of Hypomethylating Agent-Based Therapy in Myelodysplastic Syndromes
Tapan M. Kadia et al.
SEMINARS IN ONCOLOGY (2011)
The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer
Denis Drygin et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia
Emily E. Devlin et al.
BLOOD (2010)
Ribosomopathies: human disorders of ribosome dysfunction
Anupama Narla et al.
BLOOD (2010)
Epigenetic therapy in myelodysplastic syndromes
Caterina Musolino et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2010)
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes
Kerstin-Maike Schmitz et al.
GENES & DEVELOPMENT (2010)
DNA Methylation Predicts Survival and Response to Therapy in Patients With Myelodysplastic Syndromes
Lanlan Shen et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome
Jillian L. Barlow et al.
NATURE MEDICINE (2010)
Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression
Kunju Sridhar et al.
BLOOD (2009)
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
Ying Jiang et al.
BLOOD (2009)
Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome
Ken I. Mills et al.
BLOOD (2009)
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies
Tamer E. Fandy et al.
BLOOD (2009)
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
Maria E. Figueroa et al.
BLOOD (2009)
Hematologic Response to Three Alternative Dosing Schedules of Azacitidine in Patients With Myelodysplastic Syndromes
Roger M. Lyons et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Loss of Human Ribosomal Gene CpG Methylation Enhances Cryptic RNA Polymerase II Transcription and Disrupts Ribosomal RNA Processing
Therese Gagnon-Kugler et al.
MOLECULAR CELL (2009)
The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology
Brian McStay et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2008)
Structure and function of ribosomal RNA gene chromatin
Joanna L. Birch et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Haploinsufficiency of RPS14 in 5q-syndrome is associated with deregulation of ribosomal- and translation-related genes
Andrea Pellagatti et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
RPS19 mutations in patients with Diamond-Blackfan anemia
Maria Francesca Campagnoli et al.
HUMAN MUTATION (2008)
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
Benjamin L. Ebert et al.
NATURE (2008)
Epigenetic Modulation and Other Options to Improve Outcome of Stem Cell Transplantation in MDS
N. Kroger
Hematology-American Society of Hematology Education Program (2008)
Epigenetic programming of the rRNA promoter by MBD3
Shelley E. Brown et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
Jesus Espada et al.
NUCLEIC ACIDS RESEARCH (2007)
Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
Hagop Kantarjian et al.
BLOOD (2007)
The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components
Arnaud Laferte et al.
GENES & DEVELOPMENT (2006)
DNA methylation changes after 5-aza-2′-deoxycytidine therapy in patients with leukemia
Allen S. Yang et al.
CANCER RESEARCH (2006)
Decitabine improves patient outcomes in myelodysplastic syndromes - Resuits of a Phase III randomized study
H Kantarjian et al.
CANCER (2006)
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry
M Ehrich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Characterization of DNA demethylation effects induced by 5-aza-2′-deoxycytidine in patients with myelodysplastic syndrome
C Mund et al.
CANCER RESEARCH (2005)
Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis
XJ Yuan et al.
MOLECULAR CELL (2005)
Epigenetic mechanism of rRNA gene silencing: Temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation
R Santoro et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A concerted DNA methylation/histone methylation switch regulates rRNA gene dosage control and nucleolar dominance
RJ Lawrence et al.
MOLECULAR CELL (2004)
Role of human ribosomal RNA (rRNA) promoter methylation and of Methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression
K Ghoshal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition
MS Dai et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Expression levels of DNA methyltransferase genes do not correlate with p15 INK4B gene methylation in myelodysplastic syndromes
E Aoki et al.
LEUKEMIA (2003)
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus
I Grummt
GENES & DEVELOPMENT (2003)
Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway
YP Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription
R Santoro et al.
NATURE GENETICS (2002)
Share Paper
