Related references
Note: Only part of the references are listed.APRIL promotes cell-cycle progression in primary multiple myeloma cells: influence of D-type cyclin group and translocation status
John Quinn et al.
BLOOD (2011)
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Sarah E. M. Herman et al.
BLOOD (2011)
Advances in the Biology and Treatment of Bone Disease in Multiple Myeloma
Noopur Raje et al.
CLINICAL CANCER RESEARCH (2011)
Elevated Cytokine Production Restores Bone Resorption by Human Btk-Deficient Osteoclasts
Lynett Danks et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Antiarthritis Effect of a Novel Bruton's Tyrosine Kinase (BTK) Inhibitor in Rat Collagen-Induced Arthritis and Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling: Relationships between Inhibition of BTK Phosphorylation and Efficacy
Lichuan Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis
Julie A. Di Paolo et al.
NATURE CHEMICAL BIOLOGY (2011)
DRUG DISCOVERY New Btk inhibitor holds promise
Rudi W. Hendriks
NATURE CHEMICAL BIOLOGY (2011)
Molecular Targeted Approaches in Mantle Cell Lymphoma
Marc A. Weniger et al.
SEMINARS IN HEMATOLOGY (2011)
Bone Disease From Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma: Pathogenesis, Interventions, and Future Opportunities
Alex R. Minter et al.
SEMINARS IN HEMATOLOGY (2011)
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Betty Y. Chang et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo
Kihyun Kim et al.
BRITISH JOURNAL OF HAEMATOLOGY (2010)
Effects of Denosumab in Patients With Bone Metastases With and Without Previous Bisphosphonate Exposure
Jean-Jacques Body et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
TGF-β Inhibition Restores Terminal Osteoblast Differentiation to Suppress Myeloma Growth
Kyoko Takeuchi et al.
PLOS ONE (2010)
Telomerase Inhibition Targets Clonogenic Multiple Myeloma Cells through Telomere Length-Dependent and Independent Mechanisms
Sarah K. Brennan et al.
PLOS ONE (2010)
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease
Sonia Vallet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
Lee A. Honigberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
Mariateresa Fulciniti et al.
BLOOD (2009)
APRIL is overexpressed in cancer: link with tumor progression
Jerome Moreaux et al.
BMC CANCER (2009)
Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target
Dharminder Chauhan et al.
CANCER CELL (2009)
Vicious cycle between myeloma cell binding to bone marrow stromal cells via VLA-4-VCAM-1 adhesion and macrophage inflammatory protein-1α and MIP-1β production
Masahiro Abe et al.
JOURNAL OF BONE AND MINERAL METABOLISM (2009)
Targeted Disruption of the CXCL12/CXCR4 Axis Inhibits Osteolysis in a Murine Model of Myeloma-Associated Bone Loss
Peter Diamond et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2009)
Giant osteoclasts after long-term bisphosphonate therapy: diagnostic challenges
Nidhi Jain et al.
NATURE REVIEWS RHEUMATOLOGY (2009)
Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy
Robert S. Weinstein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The Role of Tec Family Kinases in Mononuclear Phagocytes
Afitap Derya Koepruelue et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2009)
Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces aritibody-dependent cellular cytotoxicity in the bone marrow mitieu
Yu-Tzu Tai et al.
BLOOD (2008)
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals
Masahiro Shinohara et al.
CELL (2008)
The Tec family tyrosine kinase Btk regulates RANKL-induced osteoclast maturation
Seoung Hoon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 α (HIF-1α) activity:: involvement in myeloma-induced angiogenesis
Simona Colla et al.
BLOOD (2007)
MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts
Sonia Vallet et al.
BLOOD (2007)
Neutralizing B-cell-activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined Immunodeficient human multiple myeloma model
Paola Neri et al.
CLINICAL CANCER RESEARCH (2007)
Targeting MEK induces myelorna-cell cytotoxicity and inhibits osteoclastogenesis
Yu-Tzu Tai et al.
BLOOD (2007)
Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression
Michael Kline et al.
LEUKEMIA RESEARCH (2007)
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma
Yazan Alsayed et al.
BLOOD (2007)
Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment
Yu-Tzu Tai et al.
CANCER RESEARCH (2006)
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature
J Moreaux et al.
BLOOD (2005)
Elevated serum levels of stromal-derived factor-1α are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients
ACW Zannettino et al.
CANCER RESEARCH (2005)
Characterization of clonogenic multiple myeloma cells
W Matsui et al.
BLOOD (2004)
Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells
P Tassone et al.
BLOOD (2004)
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption
Y Calle et al.
BLOOD (2004)
Identification of genes regulated by Dexamethasone in multiple myeloma cells using oligonucleotide arrays
D Chauhan et al.
ONCOGENE (2002)
Signaling network of the Btk family kinases
Y Qiu et al.
ONCOGENE (2000)
Tartrate-resistant acid phosphatase 5b:: A novel serum marker of bone resorption
JM Halleen et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2000)