Related references
Note: Only part of the references are listed.The Best of Both Worlds? Bitopic Orthosteric/Allosteric Ligands of G Protein-Coupled Receptors
Celine Valant et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Molecular Mechanism of beta-Arrestin-Biased Agonism at Seven-Transmembrane Receptors
Eric Reiter et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects
R. A. Schuepbach et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)
A new era of GPCR structural and chemical biology
Sebastien Granier et al.
NATURE CHEMICAL BIOLOGY (2012)
Targeting proteinase-activated receptors: therapeutic potential and challenges
Rithwik Ramachandran et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes
Pierluigi Tricoci et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Vorapaxar in the Secondary Prevention of Atherothrombotic Events
David A. Morrow et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy
Rita Rahmeh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Biased Signaling Pathways in β2-Adrenergic Receptor Characterized by 19F-NMR
Jeffrey J. Liu et al.
SCIENCE (2012)
Diversity and modularity of G protein-coupled receptor structures
Vsevolod Katritch et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Cytoprotective-Selective Activated Protein C Attenuates Pseudomonas aeruginosa-Induced Lung Injury in Mice
Nastasha Bir et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
Biased Ligands for Better Cardiovascular Drugs Dissecting G-Protein-Coupled Receptor Pharmacology
Scott M. DeWire et al.
CIRCULATION RESEARCH (2011)
Multiple receptor-mediated functions of activated protein C
H. Weiler
HAMOSTASEOLOGIE (2011)
Serine and Metalloprotease Signaling Through PAR1 in Arterial Thrombosis and Vascular Injury
Georgios Koukos et al.
IUBMB LIFE (2011)
The Occupancy of Endothelial Protein C Receptor by its Ligand Modulates the PAR-1 Dependent Signaling Specificity of Coagulation Proteases
Alireza R. Rezaie
IUBMB LIFE (2011)
Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1
Louisa Dowal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds
Unice J. K. Soh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cytoprotective protein C pathways and implications for stroke and neurological disorders
Berislav V. Zlokovic et al.
TRENDS IN NEUROSCIENCES (2011)
The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications
Silvio Danese et al.
BLOOD (2010)
Regulation of the Protein C Anticoagulant and Antiinflammatory Pathways
A. R. Rezaie
CURRENT MEDICINAL CHEMISTRY (2010)
Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function
Nikita Minhas et al.
FASEB JOURNAL (2010)
Teaching old receptors new tricks: biasing seven-transmembrane receptors
Sudarshan Rajagopal et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Akt/GSK3 Signaling in the Action of Psychotropic Drugs
Jean-Martin Beaulieu et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2009)
Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant
Laurent O. Mosnier et al.
BLOOD (2009)
Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis by Activating PAR1 at a Cryptic Ligand Site
Vishal Trivedi et al.
CELL (2009)
The role of dynamic conformational ensembles in biomolecular recognition
David D. Boehr et al.
NATURE CHEMICAL BIOLOGY (2009)
Caveolae are required for protease-selective signaling by protease-activated receptor-1
Angela Russo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a banier-protective response in endothelial cells
Jong-Sup Bae et al.
BLOOD (2007)
'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage
Nicole C. Kaneider et al.
NATURE IMMUNOLOGY (2007)
Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells
Jong-Sup Bae et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo
M. Germana Sanna et al.
NATURE CHEMICAL BIOLOGY (2006)
Protease-activated receptors in hemostasis, thrombosis and vascular biology
SR Coughlin
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Activated protein C mediates novel lung endothelial barrier enhancement - Role of sphingosine 1-phosphate receptor transactivation
JH Finigan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation
C Feistritzer et al.
BLOOD (2005)
Activated protein C variants with normal cytoprotective but reduced anticoagulant activity
LO Mosnier et al.
BLOOD (2004)
Substrate-assisted catalysis of the PAR1 thrombin receptor - Enhancement of macromolecular association and cleavage
SL Jacques et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Thrombin signalling and protease-activated receptors
SR Coughlin
NATURE (2000)
Share Paper
