3.8 Article

Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM Ac-2033D

Journal

GENOME ANNOUNCEMENTS
Volume 3, Issue 1, Pages -

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/genomeA.01406-14

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Funding

  1. Russian Foundation for Basic Research [14-04-31089]

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Nocardioides simplex VKM Ac-2033D is an effective microbial catalyst for 3-ketosteroid 1(2)-dehydrogenation, and it is capable of effective reduction of carbonyl groups at C-17 and C-20, hydrolysis of acetylated steroids, and utilization of natural sterols. Here, the complete genome sequence is reported. An array of genes related to steroid metabolic pathways have been identified.

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