Related references
Note: Only part of the references are listed.PKC inhibitors: potential in T cell-dependent immune diseases
Gottfried Baier et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
Transcriptional regulatory networks in Th17 cell differentiation
Liang Zhou et al.
CURRENT OPINION IN IMMUNOLOGY (2009)
Modulation of Th17 development and function by activation of the aryl hydrocarbon receptor - the role of endogenous ligands
Brigitta Stockinger et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12
Edda G. Schulz et al.
IMMUNITY (2009)
FOXP3 Inhibits Activation-Induced NFAT2 Expression in T Cells Thereby Limiting Effector Cytokine Expression
Troy R. Torgerson et al.
JOURNAL OF IMMUNOLOGY (2009)
The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation
Jean-Pierre Evenou et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion
Javier Arias-Diaz et al.
LABORATORY INVESTIGATION (2009)
A distal cis-regulatory element, CNS-9, controls NFAT1 and IRF4-mediated IL-10 gene activation in T helper cells
Choong-Gu Lee et al.
MOLECULAR IMMUNOLOGY (2009)
Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4+ T cells
Kazue Kogina et al.
MOLECULES AND CELLS (2009)
Mina, an Il4 repressor, controls T helper type 2 bias
Mariko Okamoto et al.
NATURE IMMUNOLOGY (2009)
The different faces of Notch in T-helper-cell differentiation
Derk Amsen et al.
NATURE REVIEWS IMMUNOLOGY (2009)
RUNX proteins in transcription factor networks that regulate T-cell lineage choice
Amelie Collins et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Initiation and maintenance of Th2 cell identity
Toshinori Nakayama et al.
CURRENT OPINION IN IMMUNOLOGY (2008)
IL-2 activation of STAT5 enhances production of IL-10 from human cytotoxic regulatory T cells, HOZOT
Kazue Tsuji-Takayama et al.
EXPERIMENTAL HEMATOLOGY (2008)
The nuclear orphan receptor NR2176 suppresses lymphocyte activation and T helper 17-dependent autoimmunity
Natascha Hermann-Kleiter et al.
IMMUNITY (2008)
Th17 cell differentiation: The long and winding road
Mandy J. McGeachy et al.
IMMUNITY (2008)
Th17 cells: a new fate for differentiating helper T cells
Zhi Chen et al.
IMMUNOLOGIC RESEARCH (2008)
The PKC inhibitor AEB071 may be a therapeutic option for psoriasis
Hans Skvara et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Autoregulation of Th1-mediated inflammation by twist1
Uwe Niesner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis
Benno Weigmann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Glucocorticoid-induced TNF receptor expression by T cells is reciprocally regulated by NF-κB and NFAT
Yifan Zhan et al.
JOURNAL OF IMMUNOLOGY (2008)
Specifying Helper T Cell Fates During Immunity
&NA;
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2008)
BRG1-Mediated Chromatin Remodeling Regulates Differentiation and Gene Expression of T Helper Cells
Andrea L. Wurster et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
NATURE (2008)
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
Francisco J. Quintana et al.
NATURE (2008)
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
Liang Zhou et al.
NATURE (2008)
Differentiation of human TH-17 cells does require TGF-β!
Anne O'Garra et al.
NATURE IMMUNOLOGY (2008)
Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells
Fuping Zhang et al.
NATURE IMMUNOLOGY (2008)
CD4 cell-secreted, posttranslationally modified cytokine GIF suppresses Th2 responses by inhibiting the initiation of IL-4 production
Misa Kim-Saijo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
Yukiko Tone et al.
NATURE IMMUNOLOGY (2008)
IL-22 is expressed by TH17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis
Katharina Kreymborg et al.
JOURNAL OF IMMUNOLOGY (2007)
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner
Lai Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT
Hui Hu et al.
TRENDS IN IMMUNOLOGY (2007)
Signalling to transcription:: Store-operated Ca2+ entry and NFAT activation in lymphocytes
Yousang Gwack et al.
CELL CALCIUM (2007)
The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo
C. Libetta et al.
KIDNEY INTERNATIONAL (2007)
New twists of T cell fate:: control of T cell activation and tolerance by TGF-β and NFAT
Mark S. Sundrud et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
NF90 regulates inducible IL-2 gene expression in T cells
Lingfang Shi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
Masahiro Ono et al.
NATURE (2007)
Th3 cells in peripheral tolerance.: II.: TGF-β-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity
Yijun Carrier et al.
JOURNAL OF IMMUNOLOGY (2007)
Peripheral CD4+ CD25+ Treg cell expansion in lung transplant recipients is not affected by calcineurin inhibitors
F. Meloni et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2006)
Cutting edge: Abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/survivin signaling pathway
Gregory Meiffren et al.
JOURNAL OF IMMUNOLOGY (2006)
Identification of common transcriptional regulatory elements in interleukin-17 target genes
Fang Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
FOXP3 and NFAT: Partners in tolerance
Alexander Y. Rudensky et al.
CELL (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production
Robert Zeiser et al.
BLOOD (2006)
Cutting edge:: Deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-β sensitivity in vitro and in vivo
EA Wohlfert et al.
JOURNAL OF IMMUNOLOGY (2006)
Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells
JJA Coenen et al.
BLOOD (2006)
Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment
H Yamane et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease
O Fainaru et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Calcium-dependent activation of interleukin-21 gene expression in T cells
HP Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
NFAT proteins: Key regulators of T-cell development and function
F Macian
NATURE REVIEWS IMMUNOLOGY (2005)
T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cells
L Fahlén et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression
DS Mehta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
CL Langrish et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Cutting edge:: TGF-β induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
MC Fantini et al.
JOURNAL OF IMMUNOLOGY (2004)
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
V Heissmeyer et al.
NATURE IMMUNOLOGY (2004)
Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes
KA Mowen et al.
MOLECULAR CELL (2004)
Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity
KM Ansel et al.
NATURE IMMUNOLOGY (2004)
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
O Brenner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-γ (PPAR-γ) ligands:: Involvement of physical association between PPAR-γ and the nuclear factor of activated T cells transcription factor
SW Chung et al.
MOLECULAR PHARMACOLOGY (2003)
Transcriptional regulation by calcium, calcineurin, and NFAT
PG Hogan et al.
GENES & DEVELOPMENT (2003)
The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression
O Komine et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
An epigenetic view of helper T cell differentiation
KM Ansel et al.
NATURE IMMUNOLOGY (2003)
Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-Bet through activation of STAT1 during initial Th1 commitment
A Takeda et al.
JOURNAL OF IMMUNOLOGY (2003)
Transcriptional mechanisms underlying lymphocyte tolerance
F Macián et al.
CELL (2002)
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
M Afkarian et al.
NATURE IMMUNOLOGY (2002)
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
J Rengarajan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
NFAT signaling: Choreographing the social lives of cells
GR Crabtree et al.
CELL (2002)
Regulation of the murine Nfatc1 gene by NFATc2
B Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naive T-H cells
J Rengarajan et al.
NATURE IMMUNOLOGY (2002)
NFAT signaling in vertebrate development
IA Graef et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2001)
Silencer activity of NFATc2 in the interleukin-12 receptor β2 proximal promoter in human T helper cells
JGI van Rietschoten et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of interferon-γ gene expression by nuclear factor of activated T cells
A Kiani et al.
BLOOD (2001)
Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein
M Iacobelli et al.
JOURNAL OF IMMUNOLOGY (2000)
Requirement for RORγ in thymocyte survival and lymphoid organ development
ZM Sun et al.
SCIENCE (2000)
Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists -: PPARγ co-association with transcription factor NFAT
XY Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun
F Macian et al.
EMBO JOURNAL (2000)