3.8 Article

Dynamic BH3 profiling-poking cancer cells with a stick

Journal

MOLECULAR & CELLULAR ONCOLOGY
Volume 3, Issue 3, Pages -

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TAYLOR & FRANCIS INC
DOI: 10.1080/23723556.2015.1040144

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The vast majority of efforts in precision medicine for cancer try to link static genetic information to tumor biology and from there predict clinical response. Dynamic BH3 profiling offers an alternative functional approach by measuring death signaling induced by specific drugs in tumors from patients ex vivo to predict clinical response.

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