Journal
BLOOD
Volume 113, Issue 6, Pages 1208-1208Publisher
AMER SOC HEMATOLOGY
DOI: 10.1182/blood-2008-11-189738
Keywords
-
Categories
Ask authors/readers for more resources
In this issue of Blood, Yamazaki and colleagues show that TGF-beta inhibits cytokine-mediated LRC clustering in purified HSCs freshly isolated from the bone marrow and induces hibernation of HSCs ex vivo. Since cytokine stimulation of LRC is important to stimulate proliferation of HSCs, the authors propose that TGF-beta may be a hibernation/quiescence regulator in the HSC bone marrow niche.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available