Journal
CASE REPORTS IN ONCOLOGY
Volume 9, Issue 1, Pages 182-187Publisher
KARGER
DOI: 10.1159/000444746
Keywords
Hepatoid adenocarcinoma; Duodenum; Carcinoembryonic antigen; alpha-Fetoprotein; Immunohistochemistry; Morphology; Chemotherapy
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Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor distinguished by having both hepatoid and adenomatous features, which can make the diagnosis challenging. Although it mostly originates in the stomach, several other sites of origin have been reported. We report a case of HAC originating in the duodenum, a very unusual location. We also discuss an approach to the diagnosis of HAC using morphological and immunohistochemical features, and explore possible therapeutic options. (C) 2016 The Author(s) Published by S. Karger AG, Basel
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