Related references
Note: Only part of the references are listed.Proapoptotic BH3-only protein Bim is essential for developmentally programmed death of germinal center-derived memory B cells and antibody-forming cells
Silke F. Fischer et al.
BLOOD (2007)
2-Methoxy antimycin reveals a unique mechanism for Bcl-xL inhibition
Pamela S. Schwartz et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma
Frederic Luciano et al.
BLOOD (2007)
Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia
Susan O'Brien et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Cell death in the nervous system
Dale E. Bredesen et al.
NATURE (2006)
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities
J. C. Reed
CELL DEATH AND DIFFERENTIATION (2006)
Bcl2's flexible loop domain regulates p53 binding and survival
Xingming Deng et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt
Y-H Han et al.
ONCOGENE (2006)
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
TG Bivona et al.
MOLECULAR CELL (2006)
Endoplasmic reticulum stress: cell life and death decisions
CY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
miR-15 and miR-16 induce apoptosis by targeting BCL2
A Cimmino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
O Takeuchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Apoptosis-based therapies for hematologic malignancies
JC Reed et al.
BLOOD (2005)
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
NATURE (2005)
Autophagy in metazoans: Cell survival in the land of plenty
JJ Lum et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
The role of BH3-only proteins in the immune system
A Strasser
NATURE REVIEWS IMMUNOLOGY (2005)
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
JT Opferman et al.
SCIENCE (2005)
Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies
GS Salvesen et al.
ONCOGENE (2004)
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk et al.
SCIENCE (2004)
The pathophysiology of mitochondrial cell death
DR Green et al.
SCIENCE (2004)
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
S Shimizu et al.
NATURE CELL BIOLOGY (2004)
Death by design: apoptosis, necrosis and autophagy
AL Edinger et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
JT Opferman et al.
NATURE (2003)
The Bcl-2 family: roles in cell survival and oncogenesis
S Cory et al.
ONCOGENE (2003)
Bad-deficient mice develop diffuse large B cell lymphoma
AM Ranger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Apoptosis in the development and maintenance of the immune system
JT Opferman et al.
NATURE IMMUNOLOGY (2003)
Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival
A Villunger et al.
BLOOD (2003)
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
J Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Proapoptotic BID is required for myeloid homeostasis and tumor suppression
SS Zinkel et al.
GENES & DEVELOPMENT (2003)
BID regulation by p53 contributes to chemosensitivity
JK Sax et al.
NATURE CELL BIOLOGY (2002)
Marine ovarian development is not affected by inactivation of the Bcl-2 family member Diva
HR Russell et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Keeping killers on a tight leash: transcriptional and posttranslational control of the pro-apoptotic activity of BH3-only proteins
H Puthalakath et al.
CELL DEATH AND DIFFERENTIATION (2002)
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes
P Bouillet et al.
NATURE (2002)
Apoptosis-based therapies
JC Reed
NATURE REVIEWS DRUG DISCOVERY (2002)
Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation
Z Xiang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
MC Wei et al.
SCIENCE (2001)
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
NJ Waterhouse et al.
JOURNAL OF CELL BIOLOGY (2001)
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
SJ Korsmeyer et al.
CELL DEATH AND DIFFERENTIATION (2000)
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
JL Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Nora, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
E Oda et al.
SCIENCE (2000)
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
R Eskes et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
