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Selected organophosphorus compounds with biological activity. Applications in medicine

Journal

RSC ADVANCES
Volume 6, Issue 9, Pages 7101-7112

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra25446a

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Funding

  1. National Science Centre (Poland) [2011/03/D/NZ7/03985]

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The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings of a literature review on OPs, including anticancer and antiviral agents, bisphosphonates, phosphorus analogues of amino acids and peptides, and organophosphorus metal complexes, and secondly, it will classify the compounds according to their biological activity and applications in the treatment of diseases.

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