Journal
RSC ADVANCES
Volume 6, Issue 40, Pages 33606-33610Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra02128j
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Funding
- National Natural Science Foundation of China [21462034]
- Distinguished Young Scientist Program of Shihezi University [2012ZRKXJQ06]
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An aryne-induced dearomatized phosphonylation reaction has been developed. Electron-deficient azaarenes such as quinolines, isoquinolines, phenanthroline and acridine undergo multicomponent reaction with arynes and dialkylphosphites to afford the corresponding dearomatized phosphonylated heterocycles in 50-90% yields.
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