Journal
NATURE REVIEWS CANCER
Volume 16, Issue 1, Pages 7-19Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc.2015.5
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Funding
- US National Institutes of Health [AI066897, AI068129]
- Department of Defense Congressionally Directed Breast Cancer Research Program award [W81XWH-13-1-0041]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI068129, R37AI066897] Funding Source: NIH RePORTER
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Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and highlight new therapeutic approaches for targeting NK cells in the treatment of cancer.
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