4.6 Review

Role of positron emission tomography in urological oncology

Journal

BJU INTERNATIONAL
Volume 106, Issue 11, Pages 1578-1593

Publisher

WILEY
DOI: 10.1111/j.1464-410X.2010.09510.x

Keywords

PET; prostate cancer; bladder cancer; kidney cancer; testicular cancer

Funding

  1. Urology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  2. Research in Urology Foundation (from the Spanish Urological Society A.E.U.)

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center dot A critical, non-structured review of the literature of the role of PET and PET/CT in urological oncology was conducted. center dot PET and PET/CT can play a role in the management of urological malignancies. For prostate cancer, the advances in radiotracers seems promising, with novel radiotracers yielding better diagnostic and staging results than 18F-fluorodeoxyglucose (18F-FDG). In kidney cancer, PET and PET/CT allow a proper diagnosis before the pathological examination of the surgical specimen. For testis cancer, PET and PET/CT have been shown to be useful in the management of seminoma tumours. In bladder cancer, these scans allow a better initial diagnosis for invasive cancer, while detecting occult metastases. center dot PET and its combined modality PET/CT have shown their potential in the diagnosis of urological malignancies. However, further studies are needed to establish the role of PET in the management of these diseases. Future applications of PET may involve fusion techniques such as magnetic resonance imaging with PET.

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