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Varicella-zoster virus (chickenpox) infection in pregnancy

Journal

Publisher

WILEY
DOI: 10.1111/j.1471-0528.2011.02983.x

Keywords

Chickenpox; infection; pregnancy; varicella; virus; zoster

Funding

  1. Perinatology Research Branch, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services

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Congenital varicella syndrome, maternal varicella-zoster virus pneumonia and neonatal varicella infection are associated with serious fetomaternal morbidity and, not infrequently, mortality. Vaccination against varicella-zoster virus can prevent the disease, and outbreak control limits the exposure of pregnant women to the infectious agent. Maternal varicella-zoster immunoglobulin administration before rash development, with or without antiviral medication, can modify the progression of the disease.

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