Journal
CHINESE CHEMICAL LETTERS
Volume 28, Issue 9, Pages 1829-1834Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2017.06.024
Keywords
Neurodegenerative diseases; Flavors; Nano-drug carriers
Categories
Funding
- National High Technology Research and Development Program [2016YFA0200303]
- National Natural Science Foundation of China [51373177, 51573188, 31522023]
- Beijing Municipal Science & Technology Commission [Z161100002616015]
- Beijing Natural Science Foundation [2164071]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDA09030301-3]
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Neurodegenerative disease is one of the serious diseases of the human nervous system. There is no effective way to treat neurodegenerative diseases. Flavors such as curcumin, coumarin, have attracted increasing attention due to having a beneficial therapeutic effect on Alzheimer's disease and Parkinson's disease. But the use of most drugs is limited in clinical treatment because of blood-brain barrier. The use of nano-drug carriers such as liposomes, polymer micelles, polymer nanoparticles and magnetic nanoparticles, which can carry drugs across the blood-brain barrier, has brought hope for the treatment of neurodegenerative diseases. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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