3.9 Review

Role of Cilia in Normal Pancreas Function and in Diseased States

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Identification and Manipulation of Biliary Metaplasia in Pancreatic Tumors

Kathleen E. DelGiorno et al.

GASTROENTEROLOGY (2014)

Article Biochemistry & Molecular Biology

Bardet-Biedl syndrome

Elizabeth Forsythe et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2013)

Article Multidisciplinary Sciences

Direct recording and molecular identification of the calcium channel of primary cilia

Paul G. DeCaen et al.

NATURE (2013)

Article Multidisciplinary Sciences

Primary cilia are specialized calcium signalling organelles

Markus Delling et al.

NATURE (2013)

Article Multidisciplinary Sciences

Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice

Nicolas F. Berbari et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Alstrom Syndrome: Genetics and Clinical Overview

Jan D. Marshall et al.

CURRENT GENOMICS (2012)

Article Developmental Biology

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

Jonas Ahnfelt-Ronne et al.

DEVELOPMENT (2012)

Review Pediatrics

Educational paper Ciliopathies

Carsten Bergmann

EUROPEAN JOURNAL OF PEDIATRICS (2012)

Article Biochemistry & Molecular Biology

BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes

Qihong Zhang et al.

HUMAN MOLECULAR GENETICS (2012)

Article Biochemistry & Molecular Biology

TRPC1 Protein Channel Is Major Regulator of Epidermal Growth Factor Receptor Signaling

Nicolas Tajeddine et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Cell Biology

The BBSome controls IFT assembly and turnaround in cilia

Qing Wei et al.

NATURE CELL BIOLOGY (2012)

Article Medicine, Research & Experimental

Restricted expression of somatostatin receptor 3 to primary cilia in the pancreatic islets and adenohypophysis of mice

Toshihiko Iwanaga et al.

BIOMEDICAL RESEARCH-TOKYO (2011)

Review Anatomy & Morphology

Pancreas Organogenesis: From Bud to Plexus to Gland

Fong Cheng Pan et al.

DEVELOPMENTAL DYNAMICS (2011)

Article Endocrinology & Metabolism

Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes

Isabel Huang-Doran et al.

DIABETES (2011)

Review Endocrinology & Metabolism

The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion

Kunitoshi Uchida et al.

ENDOCRINE JOURNAL (2011)

Article Medicine, Research & Experimental

Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease

Guy Keryer et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Cell Biology

Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers

Craig Dorrell et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2011)

Review Endocrinology & Metabolism

Alstrom syndrome: insights into the pathogenesis of metabolic disorders

Dorothee Girard et al.

NATURE REVIEWS ENDOCRINOLOGY (2011)

Article Multidisciplinary Sciences

Elevated Hedgehog/Gli signaling causes β-cell dedifferentiation in mice

Limor Landsman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Genetics & Heredity

Diabetes mellitus in Huntington disease

Lindsay A. Farrer

CLINICAL GENETICS (2010)

Article Biochemistry & Molecular Biology

Serotonin regulates pancreatic beta cell mass during pregnancy

Hail Kim et al.

NATURE MEDICINE (2010)

Review Genetics & Heredity

The primary cilium: a signalling centre during vertebrate development

Sarah C. Goetz et al.

NATURE REVIEWS GENETICS (2010)

Article Multidisciplinary Sciences

DISC1 Regulates Primary Cilia That Display Specific Dopamine Receptors

Aaron Marley et al.

PLOS ONE (2010)

Review Genetics & Heredity

Ciliary Biology: Understanding the Cellular and Genetic Basis of Human Cillopathies

Magdalena Cardenas-Rodriguez et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2009)

Article Genetics & Heredity

Making Sense of Cilia in Disease: The Human Cilloplathies

Kate Baker et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS (2009)

Article Cell Biology

LKB1 Regulates Pancreatic β Cell Size, Polarity, and Function

Zvi Granot et al.

CELL METABOLISM (2009)

Article Developmental Biology

Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia

Peng Huang et al.

DEVELOPMENT (2009)

Article Developmental Biology

Notch signaling controls liver development by regulating biliary differentiation

Yiwei Zong et al.

DEVELOPMENT (2009)

Article Biochemistry & Molecular Biology

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

Seongjin Seo et al.

HUMAN MOLECULAR GENETICS (2009)

Review Medicine, Research & Experimental

Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy

Norann A. Zaghloul et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Biochemistry & Molecular Biology

Impaired Wnt-β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

Madeline A. Lancaster et al.

NATURE MEDICINE (2009)

Article Developmental Biology

Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation

Hongjie Zhang et al.

MECHANISMS OF DEVELOPMENT (2009)

Article Multidisciplinary Sciences

Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo

Polloneal Jymmiel R. Ocbina et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process

Rajat Rohatgi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits

Chang-Xi Bai et al.

EMBO REPORTS (2008)

Article Biochemistry & Molecular Biology

The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation

C. Collet et al.

FASEB JOURNAL (2008)

Article Medicine, Research & Experimental

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

Kamal Rahmouni et al.

JOURNAL OF CLINICAL INVESTIGATION (2008)

Article Biochemistry & Molecular Biology

Pancreatic Lkb1 deletion leads to acinar polarity defects and cystic neoplasms

Aram F. Hezel et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia

Nicolas F. Berbari et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Mutations in the pericentrin (PCNT) gene cause primordial dwarfism

Anita Rauch et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2

E. Wolfgang Kuehn et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Biochemistry & Molecular Biology

Alstrom syndrome

Jan D. Marshall et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2007)

Review Cell Biology

Formation and regeneration of the endocrine pancreas

Sangeeta Dhawan et al.

CURRENT OPINION IN CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Disruption of intraflagellar in adult mice leads to transport obesity and slow-onset cystic kidney disease

James R. Davenport et al.

CURRENT BIOLOGY (2007)

Article Cell Biology

STAM and hrs down-regulate ciliary TRP receptors

Jinghua Hu et al.

MOLECULAR BIOLOGY OF THE CELL (2007)

Article Multidisciplinary Sciences

Patched1 regulates Hedgehog signaling at the primary cilium

Rajat Rohatgi et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

Maxence V. Nachury et al.

Article Biochemistry & Molecular Biology

Centrosomal localization of DNA damage checkpoint proteins

Suisheng Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia

Shixuan Wang et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

SOX9 is required for maintenance of the pancreatic progenitor cell pool

Philip A. Seymour et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Cell Biology

Distribution of pancreatic endocrine cells including IAPP-expressing cells in non-diabetic and type 2 diabetic cases

Katsumichi Iki et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)

Article Gastroenterology & Hepatology

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis

David A. Cano et al.

GASTROENTEROLOGY (2006)

Article Biochemistry & Molecular Biology

Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin

Yuliang Wu et al.

HUMAN MOLECULAR GENETICS (2006)

Article Biochemistry & Molecular Biology

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves, glucose homeostasis, and decreases TRB3

Ho-Jin Koh et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Review Endocrinology & Metabolism

The role of voltage-gated calcium channels in pancreatic β-cell physiology and pathophysiology

Shao-Nian Yang et al.

ENDOCRINE REVIEWS (2006)

Article Multidisciplinary Sciences

Platelet-derived serotonin mediates liver regeneration

M Lesurtel et al.

SCIENCE (2006)

Review Gastroenterology & Hepatology

Peutz-Jeghers syndrome and management recommendations

FM Giardiello et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Gastroenterology & Hepatology

Recurrent pancreatitis in a patient with autosomal-dominant polycystic kidney disease

Oemer Basar et al.

PANCREATOLOGY (2006)

Article Multidisciplinary Sciences

Vertebrate Smoothened functions at the primary cilium

KC Corbit et al.

NATURE (2005)

Article Neurosciences

5-HTM-mediated serotonin signaling is required for eye morphogenesis in Xenopus

S De Lucchini et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2005)

Article Biochemistry & Molecular Biology

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

M Köttgen et al.

EMBO JOURNAL (2005)

Article Medicine, Research & Experimental

Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice

QH Zhang et al.

LABORATORY INVESTIGATION (2005)

Article Endocrinology & Metabolism

Melanin-concentrating hormone receptor mutations and human obesity: Functional analysis

WT Gibson et al.

OBESITY RESEARCH (2004)

Review Cell Biology

The Wnt signaling pathway in development and disease

CY Logan et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812

YQ Cai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Hedgehog signalling in the mouse requires intraflagellar transport proteins

DW Huangfu et al.

NATURE (2003)

Article Multidisciplinary Sciences

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

SJ Ansley et al.

NATURE (2003)

Article Multidisciplinary Sciences

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

FM Lin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Genetics & Heredity

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

SM Nauli et al.

NATURE GENETICS (2003)

Review Cell Biology

Intraflagellar transport

JL Rosenbaum et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Urology & Nephrology

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

BK Yoder et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)

Article Multidisciplinary Sciences

Fusion pore dynamics and insulin granule exocytosis in the pancreatic islet

N Takahashi et al.

SCIENCE (2002)

Article Cell Biology

Polycystin-2 is an intracellular calcium release channel

P Koulen et al.

NATURE CELL BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Bending the MDCK cell primary cilium increases intracellular calcium

HA Praetorius et al.

JOURNAL OF MEMBRANE BIOLOGY (2001)

Article Multidisciplinary Sciences

Nephrocystin interacts with Pyk2, p130Cas, and tensin and triggers phosphorylation of Pyk2

T Benzing et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

Kinesin molecular motors: Transport pathways, receptors, and human disease

LSB Goldstein

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca2+ homeostasis in polycystic kidney disease

PM Vassilev et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Review Urology & Nephrology

The genetics and physiology of polycystic kidney disease

JP Calvet et al.

SEMINARS IN NEPHROLOGY (2001)

Article Multidisciplinary Sciences

Co-assembly of polycystin-1 and-2 produces unique cation-permeable currents

K Hanaoka et al.

NATURE (2000)

Article Multidisciplinary Sciences

Serotonin 2B receptor is required for heart development

CG Nebigil et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Multidisciplinary Sciences

In vitro cultivation of human islets from expanded ductal tissue

S Bonner-Weir et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Review Endocrinology & Metabolism

Molecular genetics and mechanism of autosomal dominant polycystic kidney disease

GQ Wu et al.

MOLECULAR GENETICS AND METABOLISM (2000)

Article Psychiatry

Prevalence and correlates of diabetes in national schizophrenia samples

L Dixon et al.

SCHIZOPHRENIA BULLETIN (2000)