Journal
BLOOD PURIFICATION
Volume 44, Issue 3, Pages 227-233Publisher
KARGER
DOI: 10.1159/000478967
Keywords
Cardiac surgery; Acute kidney injury; Survival rate; Chronic kidney disease; Risk factors
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Funding
- Special Foundation for Clinical Science and Technology of Jiangsu Province [BL2014080]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Jiangsu Province Natural Science Foundation [BK20151022]
- 6 Talent Peaks Project in Jiangsu Province [WSN-056]
- Blood Purification Quality Control Study of Chinese Hospital Association [CHABP2016-17]
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Background/Aims: To evaluate the long-term outcomes of Chinese patients with cardiac surgery-associated acute kidney injury (CSA-AKI). Methods: Patients who underwent cardiac surgery with a median 3-year follow-up were enrolled. The long-term survival rate and the incidence of chronic kidney disease (CKD) were recorded, and related risk factors were analyzed. Results: Of all 1,363 patients, 457 (33.5%) developed CSA-AKI. The AKI patients had a lower 3-year survival rate (88.8 vs. 97.2%, respectively, p < 0.001) and a higher incidence of CKD stages 3-5 (9.9 vs. 2.3%, respectively, p < 0.001) than the non-AKI patients. Cox regression analysis showed that AKI, atrial fibrillation, chronic cardiac insufficiency, longer surgical duration, respiratory failure after surgery, and longer mechanical ventilation time were associated with long-term mortality, while AKI, older age, and lower baseline kidney function were associated with incident CKD stages 3-5. Conclusion: CSA-AKI increased the risk of 3-year mortality and incident CKD stages 3-5. (C) 2017 S. Karger AG, Basel
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