4.4 Article

Isolation of an Acremonium sp from a screening of 52 seawater fungal isolates and preliminary characterization of its growth conditions and nematicidal activity

Journal

BIOTECHNOLOGY LETTERS
Volume 34, Issue 10, Pages 1847-1850

Publisher

SPRINGER
DOI: 10.1007/s10529-012-0967-7

Keywords

Acremonium sp.; Bursaphelenchus; Marine-derived fungi; Nematicidal compounds; Pinewood nematode

Funding

  1. National Natural Science Foundation of China [NSFC30971904]

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Fifty-two fungal isolates obtained from seawater were screened for anti-nematode activity. One isolate, an Acremonium sp., exhibited the highest activity against the pinewood nematode, Bursaphelenchus xylophilus. When it was grown at pH 7.0 and 24-26 A degrees C, nematicidal metabolites were produced. These were heat-stable, water-soluble molecules with MWs < 6 kDa. Nematicidal activity was highest at neutral pH.

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