Journal
BIOTECHNOLOGY LETTERS
Volume 34, Issue 4, Pages 683-687Publisher
SPRINGER
DOI: 10.1007/s10529-011-0815-1
Keywords
Acid stress; Cell growth; Glutathione; Leuconostoc mesenteroides
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Funding
- Korea Research Foundation [2009-0085901]
- Korea Government (MEST)
- National Research Foundation of Korea [과C6B2303, 2009-0085901] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Leuconostoc mesenteroides is a commercially important lactic acid bacterium currently used as a starter for kimchi and kefir. However, its sensitivity to acid stress limits its performance. L. mesenteroides was grown in a medium supplemented with 3.2 or 6.4 mM glutathione (GSH), and cell survival rates were measured during a long-term mild acid challenge (pH 4.0). As a result, GSH was imported by the cells and protected against acid stress; thereafter it was consumed as a nutrient. Acid stress resistance of starter cultures of this bacterium can thus be improved by cultivating it in media supplemented with GSH.
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