4.4 Article

High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica

Journal

BIOTECHNOLOGY LETTERS
Volume 31, Issue 3, Pages 377-380

Publisher

SPRINGER
DOI: 10.1007/s10529-008-9884-1

Keywords

Erythritol production; Fed-batch; Raw glycerol; Yarrowia lipolytica

Funding

  1. Ministry of Sciences and Higher Education of Poland [2P06T 044 30]

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An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l(-1) at pH 3, produced 170 g erythritol l(-1) after 7 days, corresponding to a 56% yield and a productivity of 1 g l(-1) h(-1). The Wratislavia K1 strain did not produce citric acid.

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