Journal
BIOTECHNOLOGY LETTERS
Volume 30, Issue 6, Pages 979-987Publisher
SPRINGER
DOI: 10.1007/s10529-008-9647-z
Keywords
basal expression; gene regulation; heterologous protein production; inducible promoter; Saccharomyces cerevisiae
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Saccharomyces cerevisiae is frequently used in biotechnology, including fermentative processes in food production, heterologous protein production and high throughput developments for biomedicine. Accurate expression of selected genes is essential for all these areas. Systems that can be regulated are particularly useful because they allow controlling the timing and levels of gene expression. We examine here new expression systems that have been described, including improvements of classical ones and new strategies of artificial gene control that have been applied in functional genomics.
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