4.4 Article

Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

Journal

BRAIN INJURY
Volume 31, Issue 9, Pages 1168-1176

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/02699052.2016.1274779

Keywords

United States Department of Veterans Affairs; conference; traumatic brain injury; blast-induced neurotrauma; preclinical research; experimental models

Funding

  1. Veterans Affairs [I01RX000996] Funding Source: NIH RePORTER
  2. NINDS NIH HHS [R01 NS092398, R01 NS094003] Funding Source: Medline
  3. RRD VA [I01 RX000996] Funding Source: Medline

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As a follow-up to the 2008 state-of-the-art (SQTA) conference on traumatic brain injuries (TBIs); the 2015 event organized by the United States Department of Veterans Affairs (VA) Office of Research and Development (ORD) analysed the knowledge gained Over the last 7 years as it relates to basic scientific methods, experimental findings, diagnosis. therapy, and rehabilitation of TBIs and blast-induced neurotraumas (BINTs). The current article summarizes the discussions and recommendations of the scientific panel attending the Preclinical Modeling and Therapeutic Development Workshop of the conference; with special emphasis on factors slowing research,progress and recommendations for ways of addressing the most significant pitfalls.

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