Journal
ANALYST
Volume 143, Issue 23, Pages 5799-5804Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8an01643g
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Funding
- Natural Science Foundation of China [21372032, 21778012]
- Fundamental Research Funds for the Central Universities, Beijing Municipal
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A two-photon fluorescent probe, TP-2Bz, was designed and synthesized and it exhibited good targeting capabilities toward cell nuclei. In particular, TP-2Bz demonstrated a high selectivity to both G-quadruplex DNA and viscosity inside the nucleus with significant ratiometric enhancement in fluorescence, providing a specific, versatile imaging tool for analyzing the viscosity and G-quadruplex DNA in living cells.
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