4.5 Review

Polylactic acid (PLA): Research, development and industrialization

Journal

BIOTECHNOLOGY JOURNAL
Volume 5, Issue 11, Pages 1125-1136

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/biot.201000135

Keywords

Biodegradable; Catalyst; Copolymer; Lactide; Polyester

Funding

  1. National Natural Science Foundation of China [20904053, 20974109, 20774092, 50733003]
  2. Ministry of Science and Technology of China [2007BAE42B02]
  3. Chinese Academy of Sciences [KGCX-YW-208, KJCX2-YW-H19]

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Polylactide (PLA) is a biodegradable, aliphatic polyester derived from lactic acid. It has similar mechanical properties to polyethylene terephthalate, but has a significantly lower maximum continuous use temperature. PLA products can be recycled after use either by remelting and processing the material a second time or by hydrolyzing to lactic acid, the basic chemical. In this review, the technologies for polymerization of the lactic acid and the comparison of physical, thermal and mechanical properties, biodegradability, and biocompatibility of the PLA and copolymers with other similar polymers are described.

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