Journal
BIOTECHNOLOGY AND BIOENGINEERING
Volume 111, Issue 3, Pages 441-453Publisher
WILEY
DOI: 10.1002/bit.25160
Keywords
nanocomposite hydrogels; nanoparticles; biomedical applications; tissue engineering; drug delivery
Categories
Funding
- National Institutes of Health (NCI)
- Center for Oncophysics Grant [CTO PSOC U54-CA-143837, 1 R01 EB000246-21, 1 R21 EB012726-01]
- National Science Foundation [CBET 10-33746]
- Bill & Melinda Gates Foundation
- Pratt Foundation
- US Army Engineer Research and Development Center
- Institute for Soldier Nanotechnology
- NIH [EB009196, DE019024, EB007249, HL099073, AR057837]
- National Science Foundation (NSF CAREER award)
Ask authors/readers for more resources
Hydrogels mimic native tissue microenvironment due to their porous and hydrated molecular structure. An emerging approach to reinforce polymeric hydrogels and to include multiple functionalities focuses on incorporating nanoparticles within the hydrogel network. A wide range of nanoparticles, such as carbon-based, polymeric, ceramic, and metallic nanomaterials can be integrated within the hydrogel networks to obtain nanocomposites with superior properties and tailored functionality. Nanocomposite hydrogels can be engineered to possess superior physical, chemical, electrical, and biological properties. This review focuses on the most recent developments in the field of nanocomposite hydrogels with emphasis on biomedical and pharmaceutical applications. In particular, we discuss synthesis and fabrication of nanocomposite hydrogels, examine their current limitations and conclude with future directions in designing more advanced nanocomposite hydrogels for biomedical and biotechnological applications. Biotechnol. Bioeng. 2014;111: 441-453. (c) 2013 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available