Related references
Note: Only part of the references are listed.ERAD substrates: Which way out?
Daniel N. Hebert et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
UDP-GlC:glycoprotein glucosyltransferase-glucosidase II, the ying-yang of the ER quality control
Cecilia D'Alessio et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
Protein quality control in the ER: The recognition of misfolded proteins
Pekka Maattanen et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction
Sanjeev Gupta et al.
PLOS BIOLOGY (2010)
ER and aging-Protein folding and the ER stress response
Nirinjini Naidoo
AGEING RESEARCH REVIEWS (2009)
pXBP1(U), a Negative Regulator of the Unfolded Protein Response Activator pXBP1(S), Targets ATF6 but not ATF4 in Proteasome-mediated Degradation
Hiderou Yoshida et al.
CELL STRUCTURE AND FUNCTION (2009)
A Model of the Unfolded Protein Response: Pancreatic beta-Cell as a Case Study
Santiago Schnell
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2009)
Endoplasmic reticulum stress in β-cells and development of diabetes
Sonya G. Fonseca et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis
Suchita Markan et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α
Fernanda Lisbona et al.
MOLECULAR CELL (2009)
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
Claudio Hetz et al.
MOLECULAR CELL (2009)
PERK-dependent regulation of IAP translation during ER stress
R. B. Hamanaka et al.
ONCOGENE (2009)
PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis
J. J. Gu et al.
ONCOGENE (2009)
Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP
Min Ni et al.
PLOS ONE (2009)
Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL
Shannon O'Connor et al.
PROTEIN EXPRESSION AND PURIFICATION (2009)
Assessment of cell engineering strategies for improved therapeutic protein production in CHO cells
Chaya Mohan et al.
Biotechnology Journal (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
Kseniya Petrova et al.
EMBO JOURNAL (2008)
Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins
Sami Reijonen et al.
EXPERIMENTAL CELL RESEARCH (2008)
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
Hideki Nishitoh et al.
GENES & DEVELOPMENT (2008)
AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
Dianhong Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene
Peter J. Belmont et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
An XBP-1 dependent bottle-neck in production of IgG subtype antibodies in chemically defined serum-free Chinese hamster ovary (CHO) fed-batch processes
Eric Becker et al.
JOURNAL OF BIOTECHNOLOGY (2008)
The role of the unfolded protein response in the heart
Christopher C. Glembotski
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy
Yongjie Wei et al.
MOLECULAR CELL (2008)
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Jordi Rius et al.
NATURE (2008)
From endoplasmic-reticulum stress to the inflammatory response
Kezhong Zhang et al.
NATURE (2008)
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis
Kirsten Neubert et al.
NATURE MEDICINE (2008)
Regulation of hepatic lipogenesis by the transcription factor XBP1
Ann-Hwee Lee et al.
SCIENCE (2008)
PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2α phosphorylation
Jennifer F. Raven et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A molecular chaperone inducer protects neurons from ER stress
T. Kudo et al.
CELL DEATH AND DIFFERENTIATION (2008)
The endoplasmic reticulum stress response in immunity and autoimmunity
Derrick J. Todd et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Effects of overexpression of X-box binding protein 1 on recombinant protein production in Chinese hamster ovary and NS0 myeloma cells
Sebastian C. Y. Ku et al.
BIOTECHNOLOGY AND BIOENGINEERING (2008)
In pursuit of a super producer - alternative paths to high producing recombinant mammalian cells
Gargi Seth et al.
CURRENT OPINION IN BIOTECHNOLOGY (2007)
The endoplasmic reticulum and the unfolded protein response
Jyoti D. Malhotra et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2007)
HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress
Peter Pyrko et al.
CANCER RESEARCH (2007)
Endoplasmic reticulum stress in the heart
Christopher C. Glembotski
CIRCULATION RESEARCH (2007)
Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins
Yukio Kimata et al.
JOURNAL OF CELL BIOLOGY (2007)
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
Keisuke Yamamoto et al.
DEVELOPMENTAL CELL (2007)
ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
Jun Wu et al.
DEVELOPMENTAL CELL (2007)
Nelfinavir, a lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo
JoellJ. Gills et al.
CLINICAL CANCER RESEARCH (2007)
Effects of the isoform-specific characteristics of ATF6α and ATF6β on endoplasmic reticulum stress response gene expression and cell viability
Donna J. Thuerauf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Signal integration in the endoplasmic reticulum unfolded protein response
David Ron et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
ER stress triggers apoptosis by activating BH3-only protein Bim
Hamsa Puthalakath et al.
CELL (2007)
A genome-wide transcriptional analysis of producer and non-producer NS0 myeloma cell lines
Soo Hean Gary Khoo et al.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2007)
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis
Yong Fu et al.
CANCER RESEARCH (2007)
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II)
Eriko Fujita et al.
HUMAN MOLECULAR GENETICS (2007)
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Y. Kouroku et al.
CELL DEATH AND DIFFERENTIATION (2007)
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-β, and Bcl-2
Maria Hoyer-Hansen et al.
MOLECULAR CELL (2007)
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
Sebastian Bernales et al.
PLOS BIOLOGY (2006)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
Peter S. Gargalovic et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Endoplasmic reticulum stress triggers autophagy
Tomohiro Yorimitsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload
Seiichi Oyadomari et al.
CELL (2006)
Protection of Bcl-2 by salubrinal
David Kessel
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes
Donna J. Thuerauf et al.
CIRCULATION RESEARCH (2006)
Mammalian cell factories for efficient and stable protein expression
Louise M. Barnes et al.
CURRENT OPINION IN BIOTECHNOLOGY (2006)
Bcl-2 phosphorylation by p38 MAPK - Identification of target sites and biologic consequences
Giovanna De Chiara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Ischemic preconditioning protects cardiomyocytes against ischemic injury by inducing GRP78
Kaori Shintani-Ishida et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Translating tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways
Constantinos Koumenis et al.
MOLECULAR CANCER RESEARCH (2006)
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells
T Yamada et al.
HUMAN MOLECULAR GENETICS (2006)
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1α
C Hetz et al.
SCIENCE (2006)
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
M Saleh et al.
NATURE (2006)
Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo
Ursula Unterberger et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1α-mediated NF-κB activation and down-regulation of TRAF2 expression
P Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
M Koritzinsky et al.
EMBO JOURNAL (2006)
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response
B Tirosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
ER stress and neurodegenerative diseases
D Lindholm et al.
CELL DEATH AND DIFFERENTIATION (2006)
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury
B Bailly-Maitre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Intracellular inclusions containing mutant α1-antitrypsin Z are propagated in the absence of autophagic activity
T Kamimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells
L Shao et al.
LIFE SCIENCES (2006)
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
H Yoshida et al.
JOURNAL OF CELL BIOLOGY (2006)
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
KZ Zhang et al.
CELL (2006)
Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells
AC Ranganathan et al.
CANCER RESEARCH (2006)
tRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality
Nadia Corazza et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Targeting endo-plasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL
JS Carew et al.
BLOOD (2006)
Mediators of endoplasmic reticulum stress-induced apoptosis
Eva Szegezdi et al.
EMBO REPORTS (2006)
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells
ST Nawrocki et al.
CANCER RESEARCH (2005)
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic β-cells
SG Fonseca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Functional polymorphisms of HSPA5: Possible association with bipolar disorder
C Kakiuchi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Lysosomes and autophagy in cell death control
G Kroemer et al.
NATURE REVIEWS CANCER (2005)
Autophagy and signaling: their role in cell survival and cell death
P Codogno et al.
CELL DEATH AND DIFFERENTIATION (2005)
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
MX Bi et al.
EMBO JOURNAL (2005)
The unfolded protein response is activated in Alzheimer's disease
JJM Hoozemans et al.
ACTA NEUROPATHOLOGICA (2005)
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags
DN Hebert et al.
TRENDS IN CELL BIOLOGY (2005)
A selective inhibitor-of eIF2α dephosphorylation protects cells from ER stress
M Boyce et al.
SCIENCE (2005)
Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons
A Verkhratsky
PHYSIOLOGICAL REVIEWS (2005)
Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2
T Hiroi et al.
PHARMACOGENOMICS JOURNAL (2005)
A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation
S Olivari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Fast folding of the two-domain Semliki forest virus capsid protein explains co-translational proteolytic activity
IE Sánchez et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Bcl-2 and calcium: controversy beneath the surface
CW Distelhorst et al.
ONCOGENE (2004)
Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP
S Tajiri et al.
CELL DEATH AND DIFFERENTIATION (2004)
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
B Levine et al.
DEVELOPMENTAL CELL (2004)
Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response
M Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
S Kebache et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Caspase cleavage of BiMEL triggers a positive feedback amplification of apoptotic signaling
D Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Molecular mechanisms of translational control
F Gebauer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
L Romero-Ramirez et al.
CANCER RESEARCH (2004)
Effect on tumor cells of blocking survival response to glucose deprivation
HR Park et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2004)
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
DT Nguyên et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Induction of neuronal death by ER stress in Alzheimer's disease
T Katayama et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2004)
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction - Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis
K Okada et al.
CIRCULATION (2004)
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin
S Cichon et al.
NATURE GENETICS (2004)
Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
RV Rao et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
[Anonymous]
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Production of recombinant protein therapeutics in cultivated mammalian cells
FM Wurm
NATURE BIOTECHNOLOGY (2004)
HSP70 and GRP78 induced by endothelin-1 pretreatment enhance tolerance to hypoxia in cultured neonatal rat cardiomyocytes
YX Pan et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus-secretion coupling in insulin secretion
H Ishihara et al.
HUMAN MOLECULAR GENETICS (2004)
The endoplasmic reticulum glucosyltransferase recognizes nearly native glycoprotein folding intermediates
JJ Caramelo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation
HF Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
U Özcan et al.
SCIENCE (2004)
Roles of N-linked glycans in the endoplasmic reticulum
A Helenius et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
PD Lu et al.
JOURNAL OF CELL BIOLOGY (2004)
Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6
JS Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Amyloid-beta precursor protein processing in neurodegeneration
V Wilquet et al.
CURRENT OPINION IN NEUROBIOLOGY (2004)
Cap-dependent and cap-independent translation in eukaryotic systems
WC Merrick
GENE (2004)
Bypassing a kinase activity with an ATP-competitive drug
FR Papa et al.
SCIENCE (2003)
Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance
MJ Thomenius et al.
JOURNAL OF CELL SCIENCE (2003)
Ways of dying: multiple pathways to apoptosis
JM Adams
GENES & DEVELOPMENT (2003)
Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder
C Kakiuchi et al.
NATURE GENETICS (2003)
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress
YJ Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
AH Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
GV Putcha et al.
NEURON (2003)
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors - Role of ATP binding site in suppression of caspase-7 activation
RK Reddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
Y Kimata et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Structure and intermolecular interactions of the luminal dimerization domain of human IRE1α
CY Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2α signaling
R van Huizen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis
M Shuda et al.
JOURNAL OF HEPATOLOGY (2003)
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
K Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Quality control in the endoplasmic reticulum
L Ellgaard et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1α to the endoplasmic reticulum and promotes dephosphorylation of the α subunit of eukaryotic translation initiation factor 2
MH Brush et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Endoplasmic reticulum stress and diabetes mellitus
E Araki et al.
INTERNAL MEDICINE (2003)
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
TM Dawson et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Quality control and protein folding in the secretory pathway
ES Trombetta et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2003)
Unfolding the role of protein misfolding in neurodegenerative diseases
C Soto
NATURE REVIEWS NEUROSCIENCE (2003)
Parkin protects against the toxicity associated with mutant α-synuclein:: Proteasome dysfunction selectively affects catecholaminergic neurons
L Petrucelli et al.
NEURON (2002)
Control of PERK eIF2α kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK
W Yan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α
MG Marcu et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations
O Milhavet et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
FM LaFerla
NATURE REVIEWS NEUROSCIENCE (2002)
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
C Koumenis et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress
F Terro et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
JS Shen et al.
DEVELOPMENTAL CELL (2002)
The unfolded protein response in nutrient sensing and differentiation
RJ Kaufman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
The protein kinase/endoribonuclease IRE1α that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain
CY Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi
X Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of ER stress proteins by valproate: therapeutic implications
CD Bown et al.
BIPOLAR DISORDERS (2002)
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
B Tsai et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer
K Tobiume et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain
EM Frickel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
IREI-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
K Lee et al.
GENES & DEVELOPMENT (2002)
Complementary signaling pathways regulate the unfolded protein response and are required for C-elegans development
XH Shen et al.
CELL (2001)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine
C Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
K Morita et al.
EMBO JOURNAL (2001)
Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway
S Oyadomari et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The structure of calnexin, an ER chaperone involved in quality control of protein folding
JD Schrag et al.
MOLECULAR CELL (2001)
Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms
EV Maytin et al.
EXPERIMENTAL CELL RESEARCH (2001)
The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1
XH Zou et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
D Scheuner et al.
MOLECULAR CELL (2001)
Brain ischemia and reperfusion activates the eukaryotic initiation factor 2α kinase, PERK
R Kumar et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Diabetes mellitus and exocrine pancreatic dysfunction in Perk-/- mice reveals a role for translational control in secretory cell survival
HP Harding et al.
MOLECULAR CELL (2001)
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
I Novoa et al.
JOURNAL OF CELL BIOLOGY (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
MC Wei et al.
SCIENCE (2001)
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response
K Haze et al.
BIOCHEMICAL JOURNAL (2001)
Hsp70-DnaJ chaperone pairs prevent nitric oxide-mediated apoptosis in RAW 264.7 macrophages
T Gotoh et al.
CELL DEATH AND DIFFERENTIATION (2001)
Identification of ERSE-II, a new cis-actin element responsible for the ATF6-dependent mammalian unfolded protein response
K Kokame et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
NMR structure of the calreticulin P-domain
L Ellgaard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state
KD McCullough et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
AH Kim et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis
VM Corrigall et al.
JOURNAL OF IMMUNOLOGY (2001)
Three-dimensional structure topology of the calreticulin P-domain based on NMR assignment
L Ellgaard et al.
FEBS LETTERS (2001)
NF-kappa B: a key role in inflammatory diseases
PP Tak et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast
K Okamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye et al.
MOLECULAR CELL (2000)
LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum
JR Tyson et al.
EMBO JOURNAL (2000)
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
Y Imai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Apoptosis in neurodegenerative disorders
MP Mattson
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death
S Tanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
T Nakagawa et al.
NATURE (2000)
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
H Yoshida et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
