Related references
Note: Only part of the references are listed.Cell Line-Specific Control of Recombinant Monoclonal Antibody Production by CHO Cells
Peter M. O'Callaghan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2010)
Strategies for Selecting Recombinant CHO Cell Lines for cGMP Manufacturing: Improving the Efficiency of Cell Line Generation
Alison J. Porter et al.
BIOTECHNOLOGY PROGRESS (2010)
Repeat-induced gene silencing of L1 transgenes is correlated with differential promoter methylation
James M. Rosser et al.
GENE (2010)
DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines
Yuansheng Yang et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Functional roles for noise in genetic circuits
Avigdor Eldar et al.
NATURE (2010)
DNA methylation and gene expression
Zahava Siegfried et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2010)
Detailed Understanding of Enhanced Specific Antibody Productivity in NS0 Myeloma Cells
Soo Hean Gary Khoo et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
A Study of Monoclonal Antibody-Producing CHO Cell Lines: What Makes a Stable High Producer?
Janet Chusainow et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
Daniela Meilinger et al.
EMBO REPORTS (2009)
CpG islands - 'A rough guide'
Robert S. Illingworth et al.
FEBS LETTERS (2009)
Every Microsatellite is Different: Intrinsic DNA Features Dictate Mutagenesis of Common Microsatellites Present in the Human Genome
Kristin A. Eckert et al.
MOLECULAR CARCINOGENESIS (2009)
Mechanisms of change in gene copy number
P. J. Hastings et al.
NATURE REVIEWS GENETICS (2009)
All and only CpG containing sequences are enriched in promoters abundantly bound by RNA polymerase II in multiple tissues
Julian M. Rozenberg et al.
BMC GENOMICS (2008)
Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?
T. Clouaire et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
The bisulfite genomic sequencing used in the analysis of epigenetic states, a technique in the emerging environmental genotoxicology research
Hikoya Hayatsu
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2008)
Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency
Mark F. Stinski et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2008)
Molecular analysis of successful cell line selection in transfected GS-NS0 myeloma cells
Louise M. Barnes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2007)
Human cancers express a mutator phenotype
Jason H. Bielas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Toward more efficient protein expression
Stephan Kalwy et al.
MOLECULAR BIOTECHNOLOGY (2006)
Antibody production
John R. Birch et al.
ADVANCED DRUG DELIVERY REVIEWS (2006)
Phenotypic variation during cloning procedures: Analysis of the growth behavior of clonal cell lines
Louise M. Barnes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
Limitations to the development of humanized antibody producing Chinese hamster ovary cells using glutamine synthetase-mediated gene amplification
Seung Chul Jun et al.
BIOTECHNOLOGY PROGRESS (2006)
Genetic characterization of CHO production host DG44 and derivative recombinant cell lines
M Derouazi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Genomic DNA methylation: the mark and its mediators
RJ Klose et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells
S Schlatter et al.
BIOTECHNOLOGY PROGRESS (2005)
Diverse plasmid DNA vectors by directed molecular evolution of cytomegalovirus promoters
A Wright et al.
HUMAN GENE THERAPY (2005)
Uncoupling of cell growth and proliferation results in enhancement of productivity in p21C1P1-arrested CHO cells
JX Bi et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Molecular definition of predictive indicators of stable protein expression in recombinant NSO myeloma cells
LM Barnes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2004)
Population doubling: A simple and more accurate estimation of cell growth suppression in the in vitro assay for chromosomal aberrations that reduces irrelevant positive results
SK Greenwood et al.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2004)
Production of recombinant protein therapeutics in cultivated mammalian cells
FM Wurm
NATURE BIOTECHNOLOGY (2004)
Expression of a transgene encoded on a non-viral episomal vector is not subject to epigenetic silencing by cytosine methylation
ACW Jenke et al.
MOLECULAR BIOLOGY REPORTS (2004)
Real-time RT-PCR quantification of insulin-like growth factor (IGF)-1, IGF-1 receptor, IGF-2, IGF-2 receptor, insulin receptor, growth hormone receptor, IGF-binding proteins 1, 2 and 3 in the bovine species
MW Pfaffl et al.
DOMESTIC ANIMAL ENDOCRINOLOGY (2002)
Evidence for repeat-induced gene silencing in cultured mammalian cells: Inactivation of tandem repeats of transfected genes
MW McBurney et al.
EXPERIMENTAL CELL RESEARCH (2002)
Epigenetic codes for heterochromatin formation and silencing: Rounding up the usual suspects
EJ Richards et al.
CELL (2002)
Control of cytomegalovirus lytic gene expression by histone acetylation
JC Murphy et al.
EMBO JOURNAL (2002)
Methyl CpG-binding transcriptional proteins and repression
PA Wade
BIOESSAYS (2001)
Characterization of the stability of recombinant protein production in the GS-NS0 expression system
LM Barnes et al.
BIOTECHNOLOGY AND BIOENGINEERING (2001)
Stable and unstable transgene integration sites in the human genome: extinction of the Green Fluorescent Protein transgene in K562 cells
AR Migliaccio et al.
GENE (2000)
Evaluation of stable and highly productive gene amplified CHO cell line based on the location of amplified genes
T Yoshikawa et al.
CYTOTECHNOLOGY (2000)
CPG methylation as a mechanism for the regulation of E2F activity
MR Campanero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Amplified gene location in chromosomal DNA affected recombinant protein production and stability of amplified genes
Y Yoshikawa et al.
BIOTECHNOLOGY PROGRESS (2000)