4.7 Review

Extending the limits of Bacillus for novel biotechnological applications

Journal

BIOTECHNOLOGY ADVANCES
Volume 31, Issue 8, Pages 1543-1561

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2013.08.007

Keywords

Bacillus; Biohydrogen; Co-culture; Co-polymers; Metabolic co-operation; Polyhydroxyalkanoate; Polyhydroxybutyrate; Quorum quenching; Quorum sensing

Funding

  1. CSIR-Institute of Genomics and Integrative Biology (IGIB)
  2. CSIR-INDEPTH [BSC0111]
  3. Department of Biotechnology Government of India [DBT-BT/PR-11517/BCE/08/709/2008]
  4. National Research Foundation of Korea (NRF)
  5. Ministry of Education, Science and Technology [2012M3C5A1053339]
  6. National Research Foundation of Korea [2012M3C5A1053339] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Bacillus, generally regarded as safe, has emerged as a robust organism that can withstand adverse environmental conditions and grows easily to very high densities. Bacillus has been recognized for its biotechnological applications on an industrial scale. Recent efforts have shown the potential of Bacillus to generate biofuels (hydrogen), biopolymers (polyhydroxyalkanoates), and bioactive molecules (acyl-homoserine lactonases). Bacillus can be considered the dark horse in the race to generate sustainable energy, ecofriendly non-fossil fuel-based polymers, and bioactive molecules for use as therapeutics. (C) 2013 Elsevier Inc. All rights reserved.

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