Journal
BIOTECHNOLOGY ADVANCES
Volume 29, Issue 6, Pages 930-939Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2011.07.022
Keywords
Lactic acid; Polylactic acid; Pyruvic acid; Acrylic acid; 1,2-Propanediol; Lactate ester
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Funding
- National Natural Science Foundation of China [30821005, 31000014, 31070062]
- National Basic Research Program of China [2007CB707803]
- Chinese National Programs for High Technology Research and Development [2011AA02A207]
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Lactic acid, the most important hydroxycarboxylic acid, is now commercially produced by the fermentation of sugars present in biomass. In addition to its use in the synthesis of biodegradable polymers, lactic acid can be regarded as a feedstock for the green chemistry of the future. Different potentially useful chemicals such as pyruvic acid, acrylic acid, 1,2-propanediol, and lactate ester can be produced from lactic acid via chemical and biotechnological routes. Here, we reviewed the current status of the production of potentially valuable chemicals from lactic acid via biotechnological routes. Although some of the reactions described in this review article are still not applicable at current stage, due to their greener properties, biotechnological processes for the production of lactic acid derivatives might replace the chemical routes in the future. (C) 2011 Elsevier Inc. All rights reserved.
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