Journal
BIOTECHNOLOGY ADVANCES
Volume 29, Issue 3, Pages 365-373Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2011.01.008
Keywords
Solid-state fermentation; Agro-industrial residues; Plants; Bioactive compounds; Phenolic compounds
Categories
Funding
- Science and Technology Foundation of Portugal [SFRH/BD/40439/2007, SFRH/BPD/38212/2007]
- Mexican Council of Science and Technology [SEP-CONACYT-24348/2007-2010]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/40439/2007, SFRH/BPD/38212/2007] Funding Source: FCT
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Interest in the development of bioprocesses for the production or extraction of bioactive compounds from natural sources has increased in recent years due to the potential applications of these compounds in food, chemical, and pharmaceutical industries. In this context, solid-state fermentation (SSF) has received great attention because this bioprocess has potential to successfully convert inexpensive agro-industrial residues, as well as plants, in a great variety of valuable compounds, including bioactive phenolic compounds. The aim of this review, after presenting general aspects about bioactive compounds and SSF systems, is to focus on the production and extraction of bioactive phenolic compounds from natural sources by SSF. The characteristics of SSF systems and variables that affect the product formation by this process, as well as the variety of substrates and microorganisms that can be used in SSF for the production of bioactive phenolic compounds are reviewed and discussed. (C) 2011 Elsevier Inc. All rights reserved.
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