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Recent research trends of radio-frequency biosensors for biomolecular detection

Journal

BIOSENSORS & BIOELECTRONICS
Volume 61, Issue -, Pages 448-459

Publisher

ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2014.05.025

Keywords

Biosensor; Biomolecule; Diagnosis; Radio-frequency; Detectable limit

Funding

  1. Institute of BioMed-IT, Energy-IT and Smart-IT Technology (BEST)
  2. MSIP (Ministry of Science, ICT and Future Planning), Korea, under the C-ITRC (Convergence Information Technology Research Center) [NIPA-2014-H0401-14-1007]
  3. Brain Korea 21 plus program, Yonsei University

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This article reviews radio-frequency (RF) biosensors based on passive and/or active devices and circuits. In particular, we focus on RF biosensors designed for detection of various biomolecules such as biotin-streptavidin, DNA hybridization, IgG, and glucose. The performance of these biosensors has been enhanced by the introduction of various sensing schemes with diverse nanomaterials (e.g., carbon nanotubes, graphene oxide, magnetic and gold nanoparticles, etc.). In addition, the RF biosensing platforms that can be associated with an RF active system are discussed. Finally, the challenges of RF biosensors are presented and suggestions are made for their future direction and prospects. (C) 2014 Elsevier B.V. All rights reserved.

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