Ultrasensitive dopamine sensor based on novel molecularly imprinted polypyrrole coated carbon nanotubes

A novel electrochemical sensor using the molecularly imprinted (MIP) oxygen-containing polypyrrole (PPy) decorated carbon nanotubes (CNTs) composite was proposed for in vivo detection of dopamine (DA). The prepared sensor exhibits a remarkable sensitivity of (16.18 mu A/mu M) with a linear range of 5.0 x 10(-11)-5.0 x 10(-6) M and limit of detection as low as 1.0 x 10(-11) M in the detection of DA, which might be due to the plenty cavities for binding DA through pi-pi stacking between aromatic rings and hydrogen bonds between amino groups of DA and oxygen-containing groups of the novel PPy. (C) 2014 Elsevier B.V. All rights reserved.