Journal
BIOSENSORS & BIOELECTRONICS
Volume 42, Issue -, Pages 163-169Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2012.10.043
Keywords
Templated nanoporous carbons; Defect sites; Simultaneous determination; Uric acid; Dopamine; Ascorbic acid
Categories
Funding
- National Natural Science Foundation of China [21075048, 20543003]
- Scientific Research Foundation for Returned Overseas Chinese Scholars
- State Education Ministry of China
Ask authors/readers for more resources
Nanoporous carbon materials have attracted significant interests in the design of electrodes for electrocatalysis and biosensors. Here, three templated nanoporous carbons (TNCs) materials with substantial different specific surface area were designed and synthesized by a nanocasting method, in which mesoporous silicates and acid were used as template and catalyst, respectively. The TNCs were then used as electrode materials for simultaneous detection of dopamine (DA), ascorbic acid (AA) and uric acid (UA) at physiological pH. The correlations between specific surface area, edge-plane defect sites in TNCs and their distinguishing ability towards AA, DA, and UA were investigated. For TNCs with substantial larger specific surface area and more defect sites, the oxidation peaks of AA, DA and UA were separated well and their oxidation currents increased remarkably. A highly sensitive electrochemical sensor for simultaneous detection of those biomolecules was achieved by designing TNCs1 with the largest specific surface area and the most defect sites as the electrode material. The sensitivity of AA, DA and UA at the sensor is 0.012, 4.031, 0.605 mu A/mu M respectively. Results suggest that TNCs1 is promising in biomolecules simultaneous detection. This work may also be valuable for scientists who search for excellent carbon materials for biosensing and electrocatalysis. (C) 2012 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available