4.3 Review

Genomic biomarkers in prostate cancer

Journal

TRANSLATIONAL ANDROLOGY AND UROLOGY
Volume 7, Issue 3, Pages 459-471

Publisher

AME PUBL CO
DOI: 10.21037/tau.2018.06.02

Keywords

Prostate; prostate cancer; biomarker; prostate-specific antigen (PSA); exosome; 4kscore; decipher; Genomic Prostate Score; Prolaris; Michigan Prostate Score; prostate cancer antigen 3 (PCA3); Prostate Health Index

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Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer. The evidence base for these assays is rapidly evolving. With several commercial assays available at each stage of the disease, deciding which genomic assays are appropriate for which patients can be nuanced for physicians. In an effort to help guide these decisions in clinical practice, we aim to give an update on the current status of the biomarker field of prostate cancer.

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