Journal
NATURE PLANTS
Volume 4, Issue 3, Pages 148-151Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41477-018-0115-z
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Funding
- Institute for Basic Science [IBS-R021-D1]
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Adenine base editors (ABEs), composed of an engineered deaminase and a catalytically impaired CRISPR-Cas9 variant, are powerful new tools for targeted base editing in cells and organisms. Together with cytosine base editors (CBEs), ABEs enable single-nucleotide conversions cleanly, efficiently and reversibly without double-stranded DNA cleavage, advancing genome editing in a new dimension.
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