Journal
BIOSENSORS & BIOELECTRONICS
Volume 37, Issue 1, Pages 82-87Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2012.04.042
Keywords
Flexible; Biosensor; CVD-grown graphene; Field effect transistor; Glucose; H2O2
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Funding
- Korea Electronics Technology Institute (KETI), Korea
- Converging Research Center Program through the National Research Foundation of Korea (NRF) [2009-0083290]
- Ministry of Education, Science and Technology, Korea
- National Research Foundation of Korea [2009-0083290] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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A flexible glucose sensor using a CVD-grown graphene-based field-effect-transistor (FEE) is demonstrated. The CVD-grown graphene was functionalized with linker molecules in order to immobilize the enzymes that induce the catalytic response of glucose. Polyethylene terephthalate (PET) was employed as the substrate material to realize a flexible sensor. The fabricated graphene-based FET sensor showed ambipolar transfer characteristics. Through measurements of the Dirac point shift and differential drain-source current, the fabricated FEE sensor could detect glucose levels in the range of 3.3-10.9 mM, which mostly covers the reference range of medical examination or screen test for diabetes diagnostic. This CVD-grown graphene-based FET sensor, which provides excellent fitting to a model curve even when deformed, high resolution, and continuous real-time monitoring, holds great promise, especially for portable, wearable, and implantable glucose level monitoring applications. (C) 2012 Elsevier B.V. All rights reserved.
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