Journal
BIOSENSORS & BIOELECTRONICS
Volume 26, Issue 6, Pages 2811-2821Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2010.10.017
Keywords
Biosensor; Polyaniline; Conducting polymers; Direct electron transfer; Nanostructure; Immunosensor
Categories
Funding
- CSIR, India
- DST [GAP081132]
- DBT, Govt. of India [GAP070832]
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The present paper contains a detailed overview of recent advances relating to polyaniline (PANI) as a transducer material for biosensor applications. This conducting polymer provides enormous opportunities for binding biomolecules, tuning their bio-catalytic properties, rapid electron transfer and direct communication to produce a range of analytical signals and new analytical applications. Merging the specific nature of different biomolecules (enzymes, nucleic acids, antibodies, etc.) and the key properties of this modern conducting matrix, possible biosensor designs and their biosensing characteristics have been discussed. Efforts have been made to discuss and explore various characteristics of PANI responsible for direct electron transfer leading towards fabrication of mediator-less biosensors. (C) 2010 Elsevier B.V. All rights reserved.
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