Related references
Note: Only part of the references are listed.Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
Kasthuri Kannan et al.
Oncotarget (2015)
A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas
Sriram Venneti et al.
ACTA NEUROPATHOLOGICA (2014)
BRAF-Mutated Pleomorphic Xanthoastrocytoma is Associated with Temporal Location, Reticulin Fiber Deposition and CD34 Expression
Christian Koelsche et al.
BRAIN PATHOLOGY (2014)
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Marcel Kool et al.
CANCER CELL (2014)
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Paul A. Northcott et al.
NATURE (2014)
Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
Volker Hovestadt et al.
NATURE (2014)
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
S. C. Mack et al.
NATURE (2014)
C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma
Matthew Parker et al.
NATURE (2014)
The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
Gang Wu et al.
NATURE GENETICS (2014)
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
Pawel Buczkowicz et al.
NATURE GENETICS (2014)
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
Kathryn R. Taylor et al.
NATURE GENETICS (2014)
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma
Adam M. Fontebasso et al.
NATURE GENETICS (2014)
The Promise and Challenges of Next-Generation Genome Sequencing for Clinical Care
Katherine A. Johansen Taber et al.
JAMA INTERNAL MEDICINE (2014)
Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas BRAFV600E Mutation and Expression
Celine Chappe et al.
BRAIN PATHOLOGY (2013)
Evaluation of Histone 3 Lysine 27 Trimethylation (H3K27me3) and Enhancer of Zest 2 (EZH2) in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 in H3F3A K27M Mutant Glioblastomas
Sriram Venneti et al.
BRAIN PATHOLOGY (2013)
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma
Nataliya Zhukova et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
Vijay Ramaswamy et al.
LANCET ONCOLOGY (2013)
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
David T. W. Jones et al.
NATURE GENETICS (2013)
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
Jinghui Zhang et al.
NATURE GENETICS (2013)
Molecular genetic testing and the future of clinical genomics
Sara Huston Katsanis et al.
NATURE REVIEWS GENETICS (2013)
Clinicopathological relevance of BRAF mutations in human cancer
Sahar Pakneshan et al.
PATHOLOGY (2013)
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
Peter W. Lewis et al.
SCIENCE (2013)
The chromatin remodeller ATRX: a repeat offender in human disease
David Clynes et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN
Lynn Bjerke et al.
CANCER DISCOVERY (2013)
Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma
Cristiane M. Ida et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
Paul A. Northcott et al.
ACTA NEUROPATHOLOGICA (2012)
Molecular subgroups of medulloblastoma: the current consensus
Michael D. Taylor et al.
ACTA NEUROPATHOLOGICA (2012)
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
Xiao-Yang Liu et al.
ACTA NEUROPATHOLOGICA (2012)
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
Dong-Anh Khuong-Quang et al.
ACTA NEUROPATHOLOGICA (2012)
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
Marcel Kool et al.
ACTA NEUROPATHOLOGICA (2012)
Statistical challenges associated with detecting copy number variations with next-generation sequencing
Shu Mei Teo et al.
BIOINFORMATICS (2012)
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al.
CANCER CELL (2012)
A Mouse Model of the Most Aggressive Subgroup of Human Medulloblastoma
Daisuke Kawauchi et al.
CANCER CELL (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu et al.
NATURE (2012)
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Sevin Turcan et al.
NATURE (2012)
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Trevor J. Pugh et al.
NATURE (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Paul A. Northcott et al.
NATURE (2012)
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
Gang Wu et al.
NATURE GENETICS (2012)
Personalized mice: modelling the molecular heterogeneity of medulloblastoma
S. L. Markant et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2012)
DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues
Justin M. Craig et al.
PLOS ONE (2012)
High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing
Nikhil Wagle et al.
CANCER DISCOVERY (2012)
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
Yuchen Jiao et al.
ONCOTARGET (2012)
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
Huriye Cin et al.
ACTA NEUROPATHOLOGICA (2011)
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody
David Capper et al.
ACTA NEUROPATHOLOGICA (2011)
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
Paul A. Northcott et al.
ACTA NEUROPATHOLOGICA (2011)
Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
Genevieve Schindler et al.
ACTA NEUROPATHOLOGICA (2011)
Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma
Hendrik Witt et al.
CANCER CELL (2011)
The double face of the histone variant H3.3
Emmanuelle Szenker et al.
CELL RESEARCH (2011)
Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma
Ingrid Slade et al.
FAMILIAL CANCER (2011)
Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
Yoon-Jae Cho et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Medulloblastoma Comprises Four Distinct Molecular Variants
Paul A. Northcott et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
BRAFV600E: Implications for Carcinogenesis and Molecular Therapy
Emma R. Cantwell-Dorris et al.
MOLECULAR CANCER THERAPEUTICS (2011)
BRAF V600E Mutations Are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications
Dora Dias-Santagata et al.
PLOS ONE (2011)
Altered Telomeres in Tumors with ATRX and DAXX Mutations
Christopher M. Heaphy et al.
SCIENCE (2011)
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas
Ruth G. Tatevossian et al.
ACTA NEUROPATHOLOGICA (2010)
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Patrick S. Ward et al.
CANCER CELL (2010)
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Houtan Noushmehr et al.
CANCER CELL (2010)
Subtypes of medulloblastoma have distinct developmental origins
Paul Gibson et al.
NATURE (2010)
Cross-species genomics matches driver mutations and cell compartments to model ependymoma
Robert A. Johnson et al.
NATURE (2010)
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
Peter W. Lewis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Wnt signal transduction pathways
Yuko Komiya et al.
Organogenesis (2010)
Duplication of 7q34 in Pediatric Low-Grade Astrocytomas Detected by High-Density Single-Nucleotide Polymorphism-Based Genotype Arrays Results in a Novel BRAF Fusion Gene
Angela J. Sievert et al.
BRAIN PATHOLOGY (2009)
Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics
Sarah Fattet et al.
JOURNAL OF PATHOLOGY (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma
Robert L. Yauch et al.
SCIENCE (2009)
Tandem Duplication Producing a Novel Oncogenic BRAF Fusion Gene Defines the Majority of Pilocytic Astrocytomas
David T. W. Jones et al.
CANCER RESEARCH (2008)
Hedgehog: functions and mechanisms
Markku Varjosalo et al.
GENES & DEVELOPMENT (2008)
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
Stefan Pfister et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
Eli E. Bar et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
A Portrait of Tissue Phosphoprotein Stability in the Clinical Tissue Procurement Process
Virginia Espina et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Direct multiplexed measurement of gene expression with color-coded probe pairs
Gary K. Geiss et al.
NATURE BIOTECHNOLOGY (2008)
Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features
Marcel Kool et al.
PLOS ONE (2008)
Medulloblastoma: tumorigenesis, current clinical paradigm, and efforts to improve risk stratification
William R. Polkinghorn et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2007)
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
Steven C. Clifford et al.
CELL CYCLE (2006)
Stratification of medulloblastoma on the basis of histopathological grading
Felice Giangaspero et al.
ACTA NEUROPATHOLOGICA (2006)
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
EM Shore et al.
NATURE GENETICS (2006)
Whole genome SNP arrays using DNA derived from formalin-fixed, paraffin-embedded ovarian tumor tissue
ER Thompson et al.
HUMAN MUTATION (2005)
Targeting medulloblastoma: Small-molecule inhibitors of the sonic hedgehog pathway as potential cancer therapeutics
J Romer et al.
CANCER RESEARCH (2005)
Mutations in SUFU predispose to medulloblastoma
MD Taylor et al.
NATURE GENETICS (2002)
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools
N Norton et al.
HUMAN GENETICS (2002)
Share Paper
