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RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
K Katagiri et al.
NATURE IMMUNOLOGY (2003)
The critical cytoplasmic regions, of the αL/β2 integrin in Rap1-induced adhesion and migration
Y Tohyama et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Conformational changes in the integrin βA domain provide a mechanism for signal transduction via hybrid domain movement
AP Mould et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement
E Caveggion et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
M Shimonaka et al.
JOURNAL OF CELL BIOLOGY (2003)
Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation
YZ Tu et al.
CELL (2003)
Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins
E Ihanus et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains:: A structural prototype for diversity in integrin signaling
DA Calderwood et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Structure and allosteric regulation of the αXβ2 integrin I domain
T Vorup-Jensen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Convergence of the adhesive and fibrinolytic systems:: recognition of urokinase by integrin αMβ2 as well as by the urokinase receptor regulates cell adhesion and migration
E Pluskota et al.
BLOOD (2003)
Regulation of CD11b/CD18 (Mac-1) adhesion to fibrinogen by urokinase receptor (uPAR)
H Zhang et al.
INFLAMMATION RESEARCH (2003)
Structures of the αL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
M Shimaoka et al.
CELL (2003)
Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1
OD Perez et al.
NATURE IMMUNOLOGY (2003)
Structural determinants of integrin recognition by Talin
B Garcia-Alvarez et al.
MOLECULAR CELL (2003)
Stabilizing the integrin αM inserted domain in alternative conformations with a range of engineered disulfide bonds
M Shimaoka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The RACK1 scaffold protein: A dynamic cog in cell response mechanisms
A McCahill et al.
MOLECULAR PHARMACOLOGY (2002)
The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin β cytoplasmic domains
DG Woodside et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Integrins: Bidirectional, allosteric signaling machines
RO Hynes
CELL (2002)
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
J Takagi et al.
CELL (2002)
A structural mechanism of integrin αIIbβ3 inside-out activation as regulated by its cytoplasmic face
O Vinogradova et al.
CELL (2002)
The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1
S Santoso et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Complement receptor 3 (CD11b/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively
V Le Cabec et al.
JOURNAL OF IMMUNOLOGY (2002)
Integrin activation and structural rearrangement
J Takagi et al.
IMMUNOLOGICAL REVIEWS (2002)
The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): Potential role for Rap2 in promoting B cell migration
SJ McLeod et al.
JOURNAL OF IMMUNOLOGY (2002)
Identification of integrin αMβ2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2):: immediate-early gene products expressed in atherosclerotic lesions
JM Schober et al.
BLOOD (2002)
Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand
JP Xiong et al.
SCIENCE (2002)
Imaging synapse formation during thymocyte selection:: Inability of CD3ζ to form a stable central accumulation during negative selection
LI Richie et al.
IMMUNITY (2002)
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
N Beglova et al.
NATURE STRUCTURAL BIOLOGY (2002)
Syk is required for integrin signaling in neutrophils
A Mócsai et al.
IMMUNITY (2002)
JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes
G Ostermann et al.
NATURE IMMUNOLOGY (2002)
Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes
S Fagerholm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
E Sebzda et al.
NATURE IMMUNOLOGY (2002)
Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration
DA Calderwood et al.
NATURE CELL BIOLOGY (2001)
Superantigen-induced T Cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70
MM Morgan et al.
JOURNAL OF IMMUNOLOGY (2001)
Leukocyte integrin Mac-1 recruits toll/interleukin-1 receptor superfamily signaling intermediates to modulate NF-κB activity
C Shi et al.
CIRCULATION RESEARCH (2001)
Crystal structure of the extracellular segment of integrin αVβ3
JP Xiong et al.
SCIENCE (2001)
The N-terminal region and the mid-region complex of the integrin β2 subunit
SM Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Analysis of the mammalian talin2 gene TLN2
SJ Monkley et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation
J Grimm et al.
JOURNAL OF CELL BIOLOGY (2001)
RhoA is required for monocyte tail retraction during transendothelial migration
RA Worthylake et al.
JOURNAL OF CELL BIOLOGY (2001)
Identification of a phospholipase C-γ1 (PLC-γ1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-γ1 and NFAT
D Yablonski et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Activation of RhoA and ROCK are essential for detachment of migrating Leukocytes
J Alblas et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines
G Cinamon et al.
NATURE IMMUNOLOGY (2001)
Reversibly locking a protein fold in an active conformation with a disulfide bond:: Integrin αL I domains with high affinity and antagonist activity in vivo
M Shimaoka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
C-terminal opening mimics 'inside-out' activation of integrin α5β1
J Takagi et al.
NATURE STRUCTURAL BIOLOGY (2001)
Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin β2 subunit that restrain activation of the integrin αxβ2
Q Zang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Filamins as integrators of cell mechanics and signalling
TP Stossel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Differential roles for αMβ2 integrin clustering or activation in the control of apoptosis via regulation of Akt and ERK survival mechanisms
BB Whitlock et al.
JOURNAL OF CELL BIOLOGY (2000)
An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain
JP Xiong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Chemokines trigger immediate β2 integrin affinity and mobility changes:: Differential regulation and roles in lymphocyte arrest under flow
G Constantin et al.
IMMUNITY (2000)
Ligand binding to integrins
EF Plow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Genetic analysis of integrin function in man: LAD-1 and other syndromes
N Hogg et al.
MATRIX BIOLOGY (2000)
Human blood monocytes interact with type I collagen through αxß2 integrin (CD11c-CD18, gp150-95)
R Garnotel et al.
JOURNAL OF IMMUNOLOGY (2000)
Cytohesin-1 regulates β-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1
C Geiger et al.
EMBO JOURNAL (2000)
Identification of a urokinase receptor-integrin interaction site - Promiscuous regulator of integrin function
DI Simon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
CR3: a general purpose adhesion-recognition receptor essential for innate immunity
MRW Ehlers
MICROBES AND INFECTION (2000)
Regulatory and signaling properties of the Vav family
XR Bustelo
MOLECULAR AND CELLULAR BIOLOGY (2000)
A structural basis for integrin activation by the cytoplasmic tail of the αIIb-subunit
O Vinogradova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Structural basis of collagen recognition by integrin α2β1
J Emsley et al.
CELL (2000)
Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
K Katagiri et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)