4.4 Article

Activation of the hTAS2R14 Human Bitter-Taste Receptor by (-)-Epigallocatechin Gal late and (-)-Epicatechin Gal late

Journal

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 77, Issue 9, Pages 1981-1983

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.130329

Keywords

green tea; catechin; bitter taste; bitter taste receptor; hTAS2R14

Funding

  1. Shizuoka Prefecture Collaboration of Regional Entities for the Advancement of Technological Excellence, JST

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Tea catechins have strong bitterness and influence the taste of tea. Among the 25 human bitter-taste receptors (TAS2Rs), we found that hTAS2R14 responded to catechins, in addition to hTAS2R39, a known catechin receptor. Although hTAS2R14 responded to (-)-epicatechin gallate and (-)-epigallocatechin gallate, it did not respond to (-)-epicatechin and (-)-epigallocatechin.

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