Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 76, Issue 12, Pages 2214-2218Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.120495
Keywords
sea cucumber; lipid metabolism; obesity; lipid absorption; pancreatic lipase
Categories
Funding
- National Key Technology Research and Development Program of the Ministry of Science and Technology of China [2012BAD33B07]
- Public Science and Technology Research Funds Project for Oceans [201105029]
Ask authors/readers for more resources
Several studies had indicated that the whole body of sea cucumber had beneficial effects on lipid metabolism. However, little information has been known on the individual functions of its bioactive components, and this study was undertaken to Compare the different effects on improving lipid metabolism. The rats were assigned to seven groups: control, whole sea cucumber, saponins, polysaccharides, collagen peptides, dregs and non-saponin residues. After 28 d of feeding, the serum total cholesterol, triglyceride, high-density lipoprotein-cholesterol, and hepatic lipid concentrations were examined. The results indicated that a dietary saponin supplement significantly suppressed adipose accumulation, and reduced serum and hepatic lipids. Saponin proved to be more effective than the other isolated components, so is considered to be the main lipid-lowering component in sea cucumber. The possible mechanism by which saponins Unproved lipid metabolism was also investigated. The saponins of sea cucumber suppressed and delayed TG and TC absorption which could be related to the pancreatic lipase inhibiting effect of saponins. This may be an important mechanism to explain its lipid-lowering effect on rats.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available